EFSA Compendium of Botanicals

Draft - work in progress

Guelder rose (as plant) // Viburnum opulus L.

Family:: Caprifoliaceae
Approval state:: Approved
Number of articles retrieved:: 461
Number of processed references:: 5

Compositions

#1: scopoletin (coumarin) in roots #2: Saponins in leaves #3: Lutein epoxide in leaves #4: gallic acid in bark #5: p-coumaric acid in bark #6: eugenol in bark

Endpoint Studies

Genotoxicity

Composition #1: Jarboe, Charles H., Zirvi, Karimullah A., Nicholson, John A., Schmidt, Charlotte M. Scopoletin, as antispasmodic component of Viburnum opulus and V. Prunifolium. journal of medicinal chemistry, 1967, p. 488–489. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopoletin (coumarin) in roots

Composition #2: Petricic, Jovan., Stanic, Gordana., Holik, Ludmila. Flavonoids, saponins, tannins, and arbutin as constituents of leaves of Viburnum tinus, V. opulus, and V. lantana. acta pharmaceutica jugoslavica, 1980, p. 97–101. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in leaves

Composition #3: Czeczuga, B. Investigations of carotenoids in Embryophyta. Part 8. Autumn carotenoids in the leaves of some trees. biochemical systematics and ecology, 1986, p. 203–206. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Lutein epoxide (RF-00011263-PAR)
Additional substance description:

Neoxantin, iolaxanthin, Mutatoxathin, Flavoxanthin,luteoxanthin, Lutein, and apo-12-violaxanthin
Substance used for equivalence:

carotenoids, total (RF-00000047-NTR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

36-53
Internal remarks:

Lutein epoxide in leaves

Composition #4: Turek, Sebastian., Cisowski, Wojciech. Free and chemically bonded phenolic acids in barks of Viburnum opulus L. and Sambucus nigra L. . acta poloniae pharmaceutica, 2007, vol. 64, no. 4, p. 377–83. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

121.32
Internal remarks:

gallic acid in bark

Composition #5: Turek, Sebastian., Cisowski, Wojciech. Free and chemically bonded phenolic acids in barks of Viburnum opulus L. and Sambucus nigra L. . acta poloniae pharmaceutica, 2007, vol. 64, no. 4, p. 377–83. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Milligram/Milligram (G063A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.29
Internal remarks:

p-coumaric acid in bark

Composition #6: Eriksson, Carina., Mansson, Per E., Sjodin, Kristina., Schlyter, Fredrik. Antifeedants and Feeding Stimulants in Bark Extracts of Ten Woody Non-host Species of the Pine Weevil, Hylobius abietis . journal of chemical ecology, 2008, vol. 34, no. 10, p. 1290–1297. DOI: 10.1007/s10886-008-9525-0. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Pulverized bark extracted first in a Soxhlet apparatus with pentane followed by methanol
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

GC–MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

eugenol in bark