Nettle (as plant) // Urtica dioica L. // Urtica spp.

Family:
Urticaceae
Approval state:
Approved
Number of articles retrieved:
3176
Number of processed references:
6
Compositions
#1: Alkaloids #2: Anthraquinones #3: Tannins #4: Naphthalene #5: Furan derivatives (3,4-Dimethyl-5-pentylidene-2(5H)-furanon)e #6: Eugenol #7: Carvone #8: Lectins
Endpoint Studies
#1: Alpha-glucosidase inhibition (rabbit liver) IC50
Genotoxicity
#1: The essential oil increased chromosomal aberration rates in human lymphocyte cells. #2: The essential oil increased micronucleas frequency in human lymphocytes. #3: The prepared tea is weakly mutagenic in the Somatic Mutation and Recombination test in Drosophilia melanogaster. #4: Increased DNA strand breaks in human lymphocytes after exposure to an aqueous extract of the herb and fractions of the extract in the COMET assay
Composition #1: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings. JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #2: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings. JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #3: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings. JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #4: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Composition #5: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Composition #6: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Composition #7: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Composition #8: Timoshenko, AV., Kayser, K., Kaltner, H., Andre, S., Gabius, HJ. Binding capacities of two immunomodulatory lectins, carrier-immobilized glycoligands and steroid hormones in lung cancer and the concentration of nitrite nitrate in pleural effusions . lung cancer, 1996, vol. 14, no. 1, p. 75–84. DOI: 10.1016/0169-5002(95)00513-7. [DOI link]
Endpoint study #1: Onal, S., Timur, S., Okutucu, B., Zihnioglu, F. Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs . preparative biochemistry & biotechnology, 2005, vol. 35, no. 1, p. 29–36. DOI: 10.1081/PB-200041438. [DOI link]
Genotox #1: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Genotox #2: Gul, Suleyman., Demirci, Betul., Baser, Kemal Husnu Can., Akpulat, H. Askin., Aksu, Pinar. Chemical Composition and In Vitro Cytotoxic, Genotoxic Effects of Essential Oil from Urtica dioica L.. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2012, vol. 88, no. 5, p. 666–671. DOI: 10.1007/s00128-012-0535-9. [DOI link]
Genotox #3: GRAF, U., MORAGA, AA., CASTRO, R., DIAZCARRILLO, E. GENOTOXICITY TESTING OF DIFFERENT TYPES OF BEVERAGES IN THE DROSOPHILA WING SOMATIC MUTATION AND RECOMBINATION TEST. FOOD AND CHEMICAL TOXICOLOGY, 1994, vol. 32, no. 5, p. 423–430. DOI: 10.1016/0278-6915(94)90040-X. [DOI link]
Genotox #4: Basaran, AA., Yu, TW., Plewa, MJ., Anderson, D. An investigation of some turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 1996, vol. 16, no. 2, p. 125–138. DOI: 10.1002/(SICI)1520-6866(1996)16:2<125::AID-TCM6>3.0.CO;2-K. [DOI link]