EFSA Compendium of Botanicals

Draft - work in progress

Cowslip (as plant) // Primula veris L.

Family:: Primulaceae
Approval state:: Approved
Number of articles retrieved:: 390
Number of processed references:: 1

Compositions

#1: Primulasaponin I (roots) #2: Primulasaponin I (flowers) #3: Primulasaponin I (leaves) #4: priverosaponin B 22-acetate, primulasaponin II (roots)

Endpoint Studies

Genotoxicity

Composition #1: Muller, A., Ganzera, M., Stuppner, H. Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry . journal of chromatography a, 2006, vol. 1112, no. 1-2, p. 218–223. DOI: 10.1016/j.chroma.2005.10.067. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 50%
Substance:

Primulasaponin I (RF-00010944-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.71- 8.26
Internal remarks:

Primulasaponin I (roots)

Composition #2: Muller, A., Ganzera, M., Stuppner, H. Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry . journal of chromatography a, 2006, vol. 1112, no. 1-2, p. 218–223. DOI: 10.1016/j.chroma.2005.10.067. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 50%
Substance:

Primulasaponin I (RF-00010944-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.20- 0.28
Internal remarks:

Primulasaponin I (flowers)

Composition #3: Muller, A., Ganzera, M., Stuppner, H. Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry . journal of chromatography a, 2006, vol. 1112, no. 1-2, p. 218–223. DOI: 10.1016/j.chroma.2005.10.067. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 50%
Substance:

Primulasaponin I (RF-00010944-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.07- 3.3
Internal remarks:

Primulasaponin I (leaves)

Composition #4: Muller, A., Ganzera, M., Stuppner, H. Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry . journal of chromatography a, 2006, vol. 1112, no. 1-2, p. 218–223. DOI: 10.1016/j.chroma.2005.10.067. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 50%
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Additional substance description:

priverosaponin B 22-acetate, primulasaponin II
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.23- 1.87
Internal remarks:

priverosaponin B 22-acetate, primulasaponin II (roots)