EFSA Compendium of Botanicals

Draft - work in progress

Magnolia biondii Pamp. // Magnolia fargesii (Finet & Gagnep.) W.C.Cheng

Family:: Magnoliaceae
Approval state:: Approved
Number of articles retrieved:: 204
Number of processed references:: 6

Compositions

#1: Myrcene #2: 1,8-cineole #3: Camphor #4: 7-methoxycoumarin-6-O-β-D-glucopyranoside #5: scopoletin #6: scopolin #7: Syringin #8: Lignans (kobusin and fargesin) #9: Aschantin #10: Stigmast-4-en-3-one #11: 1,8-CINEOLE (HS-SPME) #12: CAMPHOR (GC-FID) #13: CAMPHOR (HS-SPME) #14: Neolignans

Endpoint Studies

Genotoxicity

Composition #1: Jeong, Eun Sook., Choi, Kyu-Yeol., Kim, Sun-Chun., Son, In Seop., Cho, Hwang Eui., Ahn, Su Youn., Woo, Mi Hee., Hong, Jin Tae., Moon, Dong Cheul. Pattern recognition of the herbal drug, Magnoliae flos according to their essential oil components. bulletin of the korean chemical society, 2009, p. 1121–1126. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.78-1.30
Internal remarks:

Myrcene

Composition #2: Jeong, Eun Sook., Choi, Kyu-Yeol., Kim, Sun-Chun., Son, In Seop., Cho, Hwang Eui., Ahn, Su Youn., Woo, Mi Hee., Hong, Jin Tae., Moon, Dong Cheul. Pattern recognition of the herbal drug, Magnoliae flos according to their essential oil components. bulletin of the korean chemical society, 2009, p. 1121–1126. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

16.73-34.93
Internal remarks:

1,8-cineole

Composition #3: Jeong, Eun Sook., Choi, Kyu-Yeol., Kim, Sun-Chun., Son, In Seop., Cho, Hwang Eui., Ahn, Su Youn., Woo, Mi Hee., Hong, Jin Tae., Moon, Dong Cheul. Pattern recognition of the herbal drug, Magnoliae flos according to their essential oil components. bulletin of the korean chemical society, 2009, p. 1121–1126. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.45-25.43
Internal remarks:

Camphor

Composition #4: Feng, W.-S., Wang, J.-C., He, Y.-H., Zheng, X.-K., Song, K., Zhang, Y.-L., Li, M., Zhao, W. Chemical constituents from the flower buds of Magnolia biondii Pamp.. chinese pharmaceutical journal, 2015, vol. 50, no. 24, p. 2103–2106. DOI: 10.11669/cpj.2015.24.003. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

7-methoxycoumarin-6-O-β-D-glucopyranoside from flower buds
Analytical method code:

HPLC-Decomp-HG-ICP-MS (F360A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

7-methoxycoumarin-6-O-β-D-glucopyranoside

Composition #5: Feng, W.-S., Wang, J.-C., He, Y.-H., Zheng, X.-K., Song, K., Zhang, Y.-L., Li, M., Zhao, W. Chemical constituents from the flower buds of Magnolia biondii Pamp.. chinese pharmaceutical journal, 2015, vol. 50, no. 24, p. 2103–2106. DOI: 10.11669/cpj.2015.24.003. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

scopoletin (RF-00004048-PAR)
Additional substance description:

Scopoletin from flower buds
Analytical method code:

HPLC-Decomp-HG-ICP-MS (F360A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopoletin

Composition #6: Feng, W.-S., Wang, J.-C., He, Y.-H., Zheng, X.-K., Song, K., Zhang, Y.-L., Li, M., Zhao, W. Chemical constituents from the flower buds of Magnolia biondii Pamp.. chinese pharmaceutical journal, 2015, vol. 50, no. 24, p. 2103–2106. DOI: 10.11669/cpj.2015.24.003. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Scopolin (RF-00010995-PAR)
Additional substance description:

Scopolin from flower buds
Analytical method code:

HPLC-Decomp-HG-ICP-MS (F360A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopolin

Composition #7: Feng, W.-S., Wang, J.-C., He, Y.-H., Zheng, X.-K., Song, K., Zhang, Y.-L., Li, M., Zhao, W. Chemical constituents from the flower buds of Magnolia biondii Pamp.. chinese pharmaceutical journal, 2015, vol. 50, no. 24, p. 2103–2106. DOI: 10.11669/cpj.2015.24.003. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Eleutheroside B (RF-00011069-PAR)
Additional substance description:

Syringin from flower buds
Analytical method code:

HPLC-Decomp-HG-ICP-MS (F360A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Syringin

Composition #8: Kim, Ji Sun., Kim, Jae Yeon., Lee, Hwa Jin., Lim, Hyo Jin., Lee, Da Yeon., Kim, Do Hee., Ryu, Jae-Ha. Suppression of Inducible Nitric Oxide Synthase Expression by Furfuran Lignans from Flower Buds of Magnolia fargesii in BV-2 Microglial Cells . phytotherapy research, 2010, vol. 24, no. 5, p. 748–753. DOI: 10.1002/ptr.3028. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Kobusin and fargesin from flower buds
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans (kobusin and fargesin)

Composition #9: Kim, Ji Sun., Kim, Jae Yeon., Lee, Hwa Jin., Lim, Hyo Jin., Lee, Da Yeon., Kim, Do Hee., Ryu, Jae-Ha. Suppression of Inducible Nitric Oxide Synthase Expression by Furfuran Lignans from Flower Buds of Magnolia fargesii in BV-2 Microglial Cells . phytotherapy research, 2010, vol. 24, no. 5, p. 748–753. DOI: 10.1002/ptr.3028. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

(+)-epiaschantin (RF-00011089-PAR)
Additional substance description:

Aschantin from flower buds
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Aschantin

Composition #10: Lee, Jun., Kim, Nan Hee., Nam, Joo Won., Lee, Yun Mi., Jang, Dae Sik., Kim, Young Sook., Nam, Sang Hae., Seo, Eun-Kyoung., Yang, Min Suk., Kim, Jin Sook. Scopoletin from the Flower Buds of Magnolia fargesii Inhibits Protein Glycation, Aldose Reductase, and Cataractogenesis Ex Vivo. ARCHIVES OF PHARMACAL RESEARCH, 2010, vol. 33, no. 9, p. 1317–1323. DOI: 10.1007/s12272-010-0904-z. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Sitostenone Sitostenone (RF-00010846-PAR)
Additional substance description:

Stigmast-4-en-3-one in flower buds
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Stigmast-4-en-3-one

Composition #11: Zeng, Zhi., Xie, Runqian., Zhang, Tao., Zhang, Han., Chen, Jie Yu. Analysis of Volatile Compositions of Magnolia biondii Pamp by Steam Distillation and Headspace Solid Phase Micro-extraction . journal of oleo science, 2011, vol. 60, no. 12, p. 591–596. DOI: 10.5650/jos.60.591. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Additional substance description:

1,8-cineole from flower buds
Analytical method code:

Head space - solid phase micro extraction (HS-SPME) (F378A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.23-38.02
Internal remarks:

1,8-CINEOLE (HS-SPME)

Composition #12: Zeng, Zhi., Xie, Runqian., Zhang, Tao., Zhang, Han., Chen, Jie Yu. Analysis of Volatile Compositions of Magnolia biondii Pamp by Steam Distillation and Headspace Solid Phase Micro-extraction . journal of oleo science, 2011, vol. 60, no. 12, p. 591–596. DOI: 10.5650/jos.60.591. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Additional substance description:

Camphor from flower buds
Analytical method code:

GC-FID (F040A)
Analytical method - additional description:

GC-FID + GC-MS
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.47-40.66
Internal remarks:

CAMPHOR (GC-FID)

Composition #13: Zeng, Zhi., Xie, Runqian., Zhang, Tao., Zhang, Han., Chen, Jie Yu. Analysis of Volatile Compositions of Magnolia biondii Pamp by Steam Distillation and Headspace Solid Phase Micro-extraction . journal of oleo science, 2011, vol. 60, no. 12, p. 591–596. DOI: 10.5650/jos.60.591. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Additional substance description:

Camphor from flower buds
Analytical method code:

Head space - solid phase micro extraction (HS-SPME) (F378A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.18-43.26
Internal remarks:

CAMPHOR (HS-SPME)

Composition #14: Gao, Xuemei., Shen, Yanqiong., Yang, Liying., Shu, Lidang., Li, Ganpeng., Hu, Qiu-Fen. 8-O-4 '-Neolignans from Flower Buds of Magnolia fargesii and their Biological Activities. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2012, vol. 23, no. 7, p. 1274–+. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Acetone (70%)
Substance:

neolignans (RF-00004386-PAR)
Additional substance description:

fargesiphenols A-C, polysyphorin, virolin, and rhaphidecursinol A
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Neolignans