EFSA Compendium of Botanicals

Draft - work in progress

Field horsetail (as plant) // Equisetum arvense L.

Family:: Equisetaceae
Approval state:: Approved
Number of articles retrieved:: 1451
Number of processed references:: 2

Compositions

Endpoint Studies

Genotoxicity

#1: Higher incidence of micronucleus formation in vitro .

Composition #1: Ortega Garcia, Juan A., Angulo, Mario G., Sobrino-Najul, Elias J., Soldin, Offie P., Mira, Alberto Puche., Martinez-Salcedo, Eduardo., Claudio, Luz. Prenatal exposure of a girl with autism spectrum disorder to 'horsetail' (Equisetum arvense) herbal remedy and alcohol: a case report. . journal of medical case reports, 2011, vol. 5, p. 129–129. DOI: 10.1186/1752-1947-5-129. [DOI link]

Language:

English (en)
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins

Composition #2: Ortega Garcia, Juan A., Angulo, Mario G., Sobrino-Najul, Elias J., Soldin, Offie P., Mira, Alberto Puche., Martinez-Salcedo, Eduardo., Claudio, Luz. Prenatal exposure of a girl with autism spectrum disorder to 'horsetail' (Equisetum arvense) herbal remedy and alcohol: a case report. . journal of medical case reports, 2011, vol. 5, p. 129–129. DOI: 10.1186/1752-1947-5-129. [DOI link]

Language:

English (en)
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Genotox #1: Milovanovic, Vesna., Radulovic, Niko., Todorovic, Zoran., Stankovic, Miroslava., Stojanovic, Gordana. Antioxidant, antimicrobial and genotoxicity screening of hydro-alcoholic extracts of five serbian Equisetum species . plant foods for human nutrition, 2007, vol. 62, no. 3, p. 113–119. DOI: 10.1007/s11130-007-0050-z. [DOI link]

Study category:

Genotoxicity
Type of toxicological test:

micronucleus assay (CHD051TT)
Method type:

in vitro
Guideline used:

No guideline available
Tested organism:

Human (as organism) (A056J)
Strain of test organism:

lymphocytes (CHD036ST)
Sex:

No data
Exogenous metabolic activation applied:

not applicable
Route of exposure:

OTHER (OECD0PL)
Control groups used:

yes
Endpoint measured:

DNA damage and/or repair
Is genotoxic:

Positive
Remarks on genotox study:

Higher incidence of micronucleus formation in vitro.
Internal remarks:

Higher incidence of micronucleus formation in vitro .
Internal ID:

WOS:000249460200005