Draft - work in progress
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- Eleutherococcus sessiliflorus (Rupr. & Maxim.) S.Y.Hu // Acanthopanax sessiliflorus (Rupr. & Maxim.) Seem.
Eleutherococcus sessiliflorus (Rupr. & Maxim.) S.Y.Hu // Acanthopanax sessiliflorus (Rupr. & Maxim.) Seem.
- Family:
- Araliaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 67
- Number of processed references:
- 6
Composition #1: Ciesla, Lukasz., Zaluski, Daniel., Smolarz, Helena D., Hajnos, Michal., Waksmundzka-Hajnos, Monika. HPTLC-Densitometric Method for Determination of Eleutherosides B, E, and E1 in Different Eleutherococcus Species. Journal of Chromatographic Science, 2011, p. 182–188. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol extraction
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Substance:
Acanthoside B (RF-00011066-PAR)
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Additional substance description:
Eleutheroside E1
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Dry matter (B002A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.62
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Internal remarks:
Eleutheroside E1
Composition #2: Ciesla, Lukasz., Zaluski, Daniel., Smolarz, Helena D., Hajnos, Michal., Waksmundzka-Hajnos, Monika. HPTLC-Densitometric Method for Determination of Eleutherosides B, E, and E1 in Different Eleutherococcus Species. Journal of Chromatographic Science, 2011, p. 182–188. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol extraction
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Substance:
Liriodendrin (RF-00011085-PAR)
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Additional substance description:
Eleutheroside E
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Dry matter (B002A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.05
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Internal remarks:
Eleutheroside E
Composition #3: Ciesla, Lukasz., Zaluski, Daniel., Smolarz, Helena D., Hajnos, Michal., Waksmundzka-Hajnos, Monika. HPTLC-Densitometric Method for Determination of Eleutherosides B, E, and E1 in Different Eleutherococcus Species. Journal of Chromatographic Science, 2011, p. 182–188. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol extraction
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Substance:
Eleutheroside B (RF-00011069-PAR)
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Dry matter (B002A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.55
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Internal remarks:
Eleutheroside B
Composition #4: Lee, S., Ji, J., Shin, K.H., Kim, B.-K. Sessiline, a new nitrogenous compound from the fruits of Acanthopanax sessiliflorus. Planta Medica, 2002, vol. 68, no. 10, p. 939–941. DOI: 10.1055/s-2002-34925.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH extract
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Substance:
asarinin (RF-00004158-PAR)
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Additional substance description:
(-)-sesamin
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Analytical method code:
Chromatographic tests (F015A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
(-)-sesamin
Composition #5: Lee, S., Ji, J., Shin, K.H., Kim, B.-K. Sessiline, a new nitrogenous compound from the fruits of Acanthopanax sessiliflorus. Planta Medica, 2002, vol. 68, no. 10, p. 939–941. DOI: 10.1055/s-2002-34925.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH extract
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Substance:
Hydroxymethylfurfural (RF-00000379-ORG)
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Analytical method code:
Chromatographic tests (F015A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Hydroxymethylfurfural
Composition #6: Lee, S., Ji, J., Shin, K.H., Kim, B.-K. Sessiline, a new nitrogenous compound from the fruits of Acanthopanax sessiliflorus. Planta Medica, 2002, vol. 68, no. 10, p. 939–941. DOI: 10.1055/s-2002-34925.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH extract
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Substance:
scoparone (RF-00004047-PAR)
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Analytical method code:
Chromatographic tests (F015A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
scoparone
Composition #7: Yoshizumi, K., Hirano, K., Ando, H., Hirai, Y., Ida, Y., Tsuji, T., Tanaka, T., Satouchi, K., Terao, J. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. Journal of Agricultural and Food Chemistry, 2006, vol. 54, no. 2, p. 335–341. DOI: 10.1021/jf052047f.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
hot water extraction
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Substance:
Chiisanoside (RF-00010945-PAR)
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Analytical method code:
Chromatographic tests (F015A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
4.1
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Internal remarks:
chiisanoside
Composition #8: Yoshizumi, K., Hirano, K., Ando, H., Hirai, Y., Ida, Y., Tsuji, T., Tanaka, T., Satouchi, K., Terao, J. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. Journal of Agricultural and Food Chemistry, 2006, vol. 54, no. 2, p. 335–341. DOI: 10.1021/jf052047f.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
hot water extraction
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
chiisanoside and derivatives, sessiloside
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
saponins
Composition #9: Song, Y., Deng, Y., Huang, D., Wen, J., Liu, Z., Li, F. LC-MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. Journal of Ethnopharmacology, 2012, vol. 141, no. 3, p. 957–963. DOI: 10.1016/j.jep.2012.03.034.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol–water (70:30, v/v)
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Substance:
Helioxanthin (RF-00011068-PAR)
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Analytical method code:
LC-MS/MS (F027A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Helioxanthin
Composition #10: Song, Y., Deng, Y., Huang, D., Wen, J., Liu, Z., Li, F. LC-MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. Journal of Ethnopharmacology, 2012, vol. 141, no. 3, p. 957–963. DOI: 10.1016/j.jep.2012.03.034.
[
DOI link]
-
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol–water (70:30, v/v)
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Substance:
asarinin (RF-00004158-PAR)
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Analytical method code:
LC-MS/MS (F027A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
asarinin
Composition #11: Song, Y., Deng, Y., Huang, D., Wen, J., Liu, Z., Li, F. LC-MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. Journal of Ethnopharmacology, 2012, vol. 141, no. 3, p. 957–963. DOI: 10.1016/j.jep.2012.03.034.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Savinin (RF-00011067-PAR)
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Analytical method code:
LC-MS/MS (F027A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Savinin
Composition #12: Zhao, L., An, Q., Qin, F., Xiong, Z. Short Communication: Simultaneous determination of six constituents in the fruit of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem. by HPLC-UV. Natural Product Research, 2014, vol. 28, no. 7, p. 500–502. DOI: 10.1080/14786419.2013.877904.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Liriodendrin (RF-00011085-PAR)
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Additional substance description:
Acanthoside D
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Analytical method code:
HPLC-UV (F021A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
105.6-211
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Internal remarks:
Acanthoside D
Composition #13: Zhao, L., An, Q., Qin, F., Xiong, Z. Short Communication: Simultaneous determination of six constituents in the fruit of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem. by HPLC-UV. Natural Product Research, 2014, vol. 28, no. 7, p. 500–502. DOI: 10.1080/14786419.2013.877904.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Scopolin (RF-00010995-PAR)
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Additional substance description:
in mature fruits
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Analytical method code:
HPLC-UV (F021A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
143.4
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Internal remarks:
Scopolin
Composition #14: Zhao, L., An, Q., Qin, F., Xiong, Z. Short Communication: Simultaneous determination of six constituents in the fruit of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem. by HPLC-UV. Natural Product Research, 2014, vol. 28, no. 7, p. 500–502. DOI: 10.1080/14786419.2013.877904.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water-saturated n-butanol
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Substance:
Acanthoside B (RF-00011066-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
95.6-180.8
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Internal remarks:
Acanthoside B
Composition #15: Zaluski, Daniel., Smolarz, Helena Danuta., Szpilewska, Monika. Eleutherosides in Aerial Parts of Eleutherococcus Species Cultivated in Poland. JOURNAL OF AOAC INTERNATIONAL, 2011, vol. 94, no. 5, p. 1422–1426. DOI: 10.5740/jaoacint.10-185.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol extraction
-
Substance:
Liriodendrin (RF-00011085-PAR)
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Additional substance description:
Eleutheroside E
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Eleutheroside E
Endpoint study
#1: Yoshizumi, K., Hirano, K., Ando, H., Hirai, Y., Ida, Y., Tsuji, T., Tanaka, T., Satouchi, K., Terao, J. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. Journal of Agricultural and Food Chemistry, 2006, vol. 54, no. 2, p. 335–341. DOI: 10.1021/jf052047f.
[
DOI link]
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Study relevance:
Human health
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Substance:
Chiisanoside (RF-00010945-PAR)
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Control groups used:
no data
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Endpoint measured:
Half maximal inhibitory concentration (CHD021EP)
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Concentration unit:
Milligram/millilitre (G191A)
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Effect concentration:
0.75
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Critical effect:
Digestive (TOX18A)
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Target tissue:
digestive: Pancreas (TT024A)
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Effect description:
lipase inhibition
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
pancreatic lipase inhibition
Endpoint study
#2: Yoshizumi, K., Hirano, K., Ando, H., Hirai, Y., Ida, Y., Tsuji, T., Tanaka, T., Satouchi, K., Terao, J. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. Journal of Agricultural and Food Chemistry, 2006, vol. 54, no. 2, p. 335–341. DOI: 10.1021/jf052047f.
[
DOI link]
-
Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
hot water extract
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Enzyme inhibition (CHD067EP)
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Concentration unit:
Milligram/millilitre (G191A)
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-
Critical effect:
Digestive (TOX18A)
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Target tissue:
digestive: Pancreas (TT024A)
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Effect description:
lipase inhibition (reduction of 30% of the lipase activity)
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
pancreatic lipase inhibition