Composition #1: Bhatt, S. K., Saxena, V. K., Singh, K. V. Stigmasta-5,24(28)-diene-3β-O-α-L-rhamnopyranosyl-O-β-D-arabinopyranoside from leaves of Cyperus scariosus R.Br. indian journal of physical and natural sciences, 1982, p. 15–17. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
steroidal saponins (RF-00010818-PAR)
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Additional substance description:
Stigmasta-5,24(28)-diene-3β-O-α-L-rhamnopyranosyl-O-β-D-arabinopyranoside
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Steroidal saponin (Stigmasta-5,24(28)-diene-3β-O-α-L-rhamnopyranosyl-O-β-D-arabinopyranoside)
Composition #2: Chowdhury, Jasim Uddin., Yusuf, Mohammed., Hossain, Muhammad Muzaffar. Aromatic plants of Bangladesh: Chemical constituents of rhizome oil of Cyperus scariosus R. Br. indian perfumer, 2005, p. 103–105. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Substance:
beta-selinene (RF-00011306-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
2.75
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Internal remarks:
Beta-selinene
Composition #3: Adams, S. John., Kuruvilla, Gina R., Krishnamurthy, K. V., Nagarajan, M., Venkatasubramanian, Padma. Pharmacognostic and phytochemical studies on Ayurvedic drugs Ativisha and Musta . revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2013, vol. 23, no. 3, p. 398–409. DOI: 10.1590/S0102-695X2013005000040.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Powder (A06JD)
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
Electron microscopical tests (F096A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Alkaloids
Composition #4: Adams, S. John., Kuruvilla, Gina R., Krishnamurthy, K. V., Nagarajan, M., Venkatasubramanian, Padma. Pharmacognostic and phytochemical studies on Ayurvedic drugs Ativisha and Musta . revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2013, vol. 23, no. 3, p. 398–409. DOI: 10.1590/S0102-695X2013005000040.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Powder (A06JD)
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Electron microscopical tests (F096A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins
Endpoint study
#1: Bhagwat, Deepak., Kharya, M. D., Bani, Sarang., Pandey, Anjali., Chauhan, Prashant Singh., Kour, Kiranjeet., Suri, K. A., Satti, N. K., Dutt, Prabhu. Cyperus scariosus Chloroform Fraction Inhibits T cell Responses in Balb/C Mice. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2009, vol. 8, no. 5, p. 399–408. .
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Study relevance:
Human health
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
chloroform fraction after extraction with 50% ethanol
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Type of toxicological test:
short-term toxicity (CHD017TT)
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Tested organism:
House mouse (as animal) (A0CNT)
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Strain of test organism:
Balb/c (CHD002ST)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
6
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Endpoint measured:
Concentration level (CHD013EP)
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Concentration unit:
Milligrams per kilogram body weight per day (G211A)
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Effect concentration:
600
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Critical effect:
IMMUNOTOXICITY (TOX09A)
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Effect description:
immunosuppression: dose-related decrease in primary antibody formation
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Effect or parameter linked to the endpoint:
immunology (CHD026BE)
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Internal remarks:
immunosuppression
