EFSA Compendium of Botanicals

Draft - work in progress

Cornus officinalis Siebold & Zucc.

Family:: Cornaceae
Approval state:: Approved
Number of articles retrieved:: 1875
Number of processed references:: 2

Compositions

#1: Elemicin #2: Furfural #3: iso-Asarone #4: Methyleugenol #5: 5-hydroxymethyl-2-furfural

Endpoint Studies

Genotoxicity

Composition #1: Miyazawa, Mitsuo., Kameoka, Hiromu. Volatile flavor components of crude drugs. Part VII. Volatile flavor components of Corni Fructus (Cornus officinalis Sieb. et Zucc.). Agricultural and Biological Chemistry, 1989, p. 3337–3340. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

additional extraction with diethyl ether
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.2
Internal remarks:

Elemicin

Composition #2: Miyazawa, Mitsuo., Kameoka, Hiromu. Volatile flavor components of crude drugs. Part VII. Volatile flavor components of Corni Fructus (Cornus officinalis Sieb. et Zucc.). Agricultural and Biological Chemistry, 1989, p. 3337–3340. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

additional extraction with diethyl ether
Substance:

Furfural (RF-1009-001-PPP)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.2
Internal remarks:

Furfural

Composition #3: Miyazawa, Mitsuo., Kameoka, Hiromu. Volatile flavor components of crude drugs. Part VII. Volatile flavor components of Corni Fructus (Cornus officinalis Sieb. et Zucc.). Agricultural and Biological Chemistry, 1989, p. 3337–3340. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

additional extraction with diethyl ether
Substance:

asarone (RF-00003698-PAR)
Additional substance description:

iso-Asarone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.1
Internal remarks:

iso-Asarone

Composition #4: Miyazawa, Mitsuo., Kameoka, Hiromu. Volatile flavor components of crude drugs. Part VII. Volatile flavor components of Corni Fructus (Cornus officinalis Sieb. et Zucc.). Agricultural and Biological Chemistry, 1989, p. 3337–3340. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

additional extraction with diethyl ether
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.4
Internal remarks:

Methyleugenol

Composition #5: Park, Chan Hum., Noh, Jeong Sook., Tanaka, Takashi., Roh, Seong-Soo., Lee, Jang Cheon., Yokozawa, Takako. Polyphenol isolated from Corni Fructus, 7sedoheptulose, modulates advanced glycation endproduct-related pathway in type 2 diabetic mice. ARCHIVES OF PHARMACAL RESEARCH, 2015, vol. 38, no. 6, p. 1270–1280. DOI: 10.1007/s12272-014-0457-7. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Hydroxymethylfurfural (RF-00000379-ORG)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5-hydroxymethyl-2-furfural