EFSA Compendium of Botanicals

Draft - work in progress

Calophyllum inophyllum L.

Family:: Calophyllaceae
Approval state:: Approved
Number of articles retrieved:: 657
Number of processed references:: 5

Compositions

#1: Tannins #2: Alkaloids in leaves #3: Alkaloids in branches #4: saponins #5: Tannins #6: Alkaloids #7: Lignans #8: Coumarins

Endpoint Studies

Genotoxicity

Composition #1: Baens, Luz., Yenko, F. M., West, Augustus P., Curran, H. M. Tannin content of Philippine barks and woods. philippine journal of science, 1934, p. 177–190. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Drying (dehydration) (A07KG)
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.39-19.12
Internal remarks:

Tannins

Composition #2: Han, Shuyun., Han, Changri. Extraction and determination of total alkaloids in Calophyllum inophyllum linn by spectrophotography. yingyong huagong, 2010, p. 1419–1421. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.172
Internal remarks:

Alkaloids in leaves

Composition #3: Han, Shuyun., Han, Changri. Extraction and determination of total alkaloids in Calophyllum inophyllum linn by spectrophotography. yingyong huagong, 2010, p. 1419–1421. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

in branches
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.074
Internal remarks:

Alkaloids in branches

Composition #4: Begum, A., Baig, M.D., Uddin, S.B., Venkateshwara Reddy, A. Evaluation and comparison of anxiolytic activity of ethanolic and aqueous leaf extracts of Calophyllum inophyllum in albino wistar rats. international journal of pharma and bio sciences, 2014, vol. 5, no. 3, p. P576–P584. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol, Water and Petroleum ether
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins

Composition #5: Begum, A., Baig, M.D., Uddin, S.B., Venkateshwara Reddy, A. Evaluation and comparison of anxiolytic activity of ethanolic and aqueous leaf extracts of Calophyllum inophyllum in albino wistar rats. international journal of pharma and bio sciences, 2014, vol. 5, no. 3, p. P576–P584. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol and water
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #6: Begum, A., Baig, M.D., Uddin, S.B., Venkateshwara Reddy, A. Evaluation and comparison of anxiolytic activity of ethanolic and aqueous leaf extracts of Calophyllum inophyllum in albino wistar rats. international journal of pharma and bio sciences, 2014, vol. 5, no. 3, p. P576–P584. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol and water
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #7: Raju, D.C., Victoria, T.D. Phytochemical screening and bioactivity studies of immature and mature leaves of Calophyllum inophyllum.L. journal of chemical and pharmaceutical sciences, 2015, vol. 8, no. 1, p. 46–51. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleum ether and ethanol on mature and immature leaves
Substance:

lignans (RF-00004361-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans

Composition #8: Itoigawa, M., Ito, C., Tan, HTW., Kuchide, M., Tokuda, H., Nishino, H., Furukawa, H. Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum . cancer letters, 2001, vol. 169, no. 1, p. 15–19. DOI: 10.1016/S0304-3835(01)00521-3. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

Apetatolide, Calocoumarins A-C, Calophyllolide, Inophyllum A, C, D & E,Isocallophyllic acid
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins