EFSA
ecomole
vscht
  2. Burdock (as plant) // Arctium lappa L. // Arctium majus (Gaertn.) Bernh.

Burdock (as plant) // Arctium lappa L. // Arctium majus (Gaertn.) Bernh.

Family:
Asteraceae (Compositae)
Approval state:
Approved
Number of articles retrieved:
1650
Number of processed references:
4
Compositions
#1: atropine #2: Arctiin (lignan) #3: arctigenin
Endpoint Studies
#1: anticholinergic poisoning #2: abortifacient agent (roots) #3: abortifacient agent (leaves)
Genotoxicity
Composition #1: Rhoads, P.M., Tong, T.G., Banner, W., Anderson, R. Anticholinergic poisonings associated with commercial burdock root tea. clinical toxicology, 1984, vol. 22, no. 6, p. 581–584. DOI: 10.3109/15563658408992587. [DOI link]
Composition #2: Wu, Jian-Guo., Wu, Jin-Zhong., Sun, Lian-Na., Han, Ting., Du, Jian., Ye, Qi., Zhang, Hong., Zhang, Yu-Guang. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats . phytomedicine, 2009, vol. 16, no. 11, p. 1033–1041. DOI: 10.1016/j.phymed.2009.04.005. [DOI link]
Composition #3: Susanti, Siti., Iwasaki, Hironori., Itokazu, Yukiyoshi., Nago, Mariko., Taira, Naoyuki., Saitoh, Seikoh., Oku, Hirosuke. Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L. . journal of natural medicines, 2012, vol. 66, no. 4, p. 614–621. DOI: 10.1007/s11418-012-0628-0. [DOI link]
Endpoint study #1: Rhoads, P.M., Tong, T.G., Banner, W., Anderson, R. Anticholinergic poisonings associated with commercial burdock root tea. clinical toxicology, 1984, vol. 22, no. 6, p. 581–584. DOI: 10.3109/15563658408992587. [DOI link]
Endpoint study #2: Shah, Ghulam Mujtaba., Khan, Mir Ajab., Ahmad, Mushtaq., Zafar, Muhammad., Khan, Aftab Ahmed. Observations on antifertility and abortifacient herbal drugs. african journal of biotechnology, 2009, vol. 8, no. 9, p. 1959–1964. .
Endpoint study #3: Shah, Ghulam Mujtaba., Khan, Mir Ajab., Ahmad, Mushtaq., Zafar, Muhammad., Khan, Aftab Ahmed. Observations on antifertility and abortifacient herbal drugs. african journal of biotechnology, 2009, vol. 8, no. 9, p. 1959–1964. .