EFSA Compendium of Botanicals

Draft - work in progress

Akebia quinata (Houtt.) Decne.

Family:: Lardizabalaceae
Approval state:: Approved
Number of articles retrieved:: 1208
Number of processed references:: 3

Compositions

#1: Triterpene saponins #2: Scopolin #3: Furfural #4: Methyleugenol #5: Eugenol #6: 2-pentylfuran #7: Carvone #8: Lignans

Endpoint Studies

Genotoxicity

Composition #1: Ling, Yun., Zhang, Yaping., Zhou, Yu., Jiang, Dengzhao., Xu, Lingling., Liao, Liang. Rapid detection and characterization of the major chemical constituents in Akebia quinata by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry. analytical methods, 2016, p. 2634–2644. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Triterpene saponins

Composition #2: Ling, Yun., Zhang, Yaping., Zhou, Yu., Jiang, Dengzhao., Xu, Lingling., Liao, Liang. Rapid detection and characterization of the major chemical constituents in Akebia quinata by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry. analytical methods, 2016, p. 2634–2644. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Scopolin (RF-00010995-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scopolin

Composition #3: Kawata, Jyunichi., Kameda, Munekazu., Miyazawa, Mitsuo. Constituents of essential oil from the dried fruits and stems of Akebia quinata (THUNB.) DECNE. . journal of oleo science, 2007, vol. 56, no. 2, p. 59–63. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Furfural (RF-1009-001-PPP)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.6
Internal remarks:

Furfural

Composition #4: Kawata, Jyunichi., Kameda, Munekazu., Miyazawa, Mitsuo. Constituents of essential oil from the dried fruits and stems of Akebia quinata (THUNB.) DECNE. . journal of oleo science, 2007, vol. 56, no. 2, p. 59–63. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.1
Internal remarks:

Methyleugenol

Composition #5: Kawata, Jyunichi., Kameda, Munekazu., Miyazawa, Mitsuo. Constituents of essential oil from the dried fruits and stems of Akebia quinata (THUNB.) DECNE. . journal of oleo science, 2007, vol. 56, no. 2, p. 59–63. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.3
Internal remarks:

Eugenol

Composition #6: Kawata, Jyunichi., Kameda, Munekazu., Miyazawa, Mitsuo. Constituents of essential oil from the dried fruits and stems of Akebia quinata (THUNB.) DECNE. . journal of oleo science, 2007, vol. 56, no. 2, p. 59–63. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

2-Pentylfuran (RF-00008482-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.7
Internal remarks:

2-pentylfuran

Composition #7: Kawata, Jyunichi., Kameda, Munekazu., Miyazawa, Mitsuo. Constituents of essential oil from the dried fruits and stems of Akebia quinata (THUNB.) DECNE. . journal of oleo science, 2007, vol. 56, no. 2, p. 59–63. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Carvone (RF-0538-001-PPP)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.1
Internal remarks:

Carvone

Composition #8: Jin, Hong-Guang., Kim, A. Ryun., Ko, Hae Ju., Lee, Sang Kook., Woo, Eun-Rhan. Three New Lignan Glycosides with IL-6 Inhibitory Activity from Akebia quinata . chemical & pharmaceutical bulletin, 2014, vol. 62, no. 3, p. 288–293. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

akeqintoside A to C, syringin
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

optical rotations, UV spectra, IR spectra, CD spectra, HR-ESI-MS, NMR spectra
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans