Composition #1: Fu Wen-Wei., Tan Chang-Heng., Lu Lu-Lu., Meng Xiang-Xue., Luo Hong-Feng., Zhu Da-Yuan. Chemical Constituents from the Root of Actinidia deliciosa. chinese journal of natural medicines, 2010, vol. 8, no. 4, p. 247–249. DOI: 10.3724/SP.J.1009.2010.00247.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
95% ethanol
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
isoscopoletin, fraxetin,aesculetin,umbelliferone,5,7-dihydroxychromone
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Coumarins (isoscopoletin, fraxetin,aesculetin,umbellierone, 5.7-dihydroxychromone)
Composition #2: Kuhnle, Gunter G. C., Dell'Aquila, Caterina., Aspinall, Sue M., Runswick, Shirley A., Joosen, Annemiek M. C. P., Mulligan, Angela A., Bingham, Sheila A. Phytoestrogen content of fruits and vegetables commonly consumed in the UK based on LC-MS and 13C-labelled standards. food chemistry, 2009, p. 542–554. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
10% methanol in sodium acetate (0.1%,pH5)
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Substance:
isoflavones (RF-00004359-PAR)
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Additional substance description:
genistein, daidzein, glycitein
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Analytical method code:
LC-MS (F026A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
<0.01
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Internal remarks:
isoflavones
Composition #3: Kuhnle, Gunter G. C., Dell'Aquila, Caterina., Aspinall, Sue M., Runswick, Shirley A., Joosen, Annemiek M. C. P., Mulligan, Angela A., Bingham, Sheila A. Phytoestrogen content of fruits and vegetables commonly consumed in the UK based on LC-MS and 13C-labelled standards. food chemistry, 2009, p. 542–554. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
10% methanol in sodium acetate (0.1%,pH 5)
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Substance:
lignans (RF-00004361-PAR)
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Additional substance description:
Secoisolariciresinol, Matairesinol
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Analytical method code:
LC-MS (F026A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.11
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Internal remarks:
Lignans (seroisolariciresinol and matairesinol
Composition #4: Pereira, Joao., Pereira, Jorge., Camara, Jose S. Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile-Identification of novel compounds . talanta, 2011, vol. 83, no. 3, p. 899–906. DOI: 10.1016/j.talanta.2010.10.064.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Additional extraction description:
headspace solid-phase microextraction
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Substance:
myrcene (RF-00003503-PAR)
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Additional substance description:
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Analytical method code:
Gaschromatography (GC) (F037A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Beta myrcene
Composition #5: Pereira, Joao., Pereira, Jorge., Camara, Jose S. Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile-Identification of novel compounds . talanta, 2011, vol. 83, no. 3, p. 899–906. DOI: 10.1016/j.talanta.2010.10.064.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Additional extraction description:
headspace solid-phase microextraction
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Substance:
Hydroxymethylfurfural (RF-00000379-ORG)
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Analytical method code:
Gaschromatography (GC) (F037A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
5-Hydroxymethylfurfural (potentially cacinogenic to humans)
Composition #6: Pereira, Joao., Pereira, Jorge., Camara, Jose S. Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile-Identification of novel compounds . talanta, 2011, vol. 83, no. 3, p. 899–906. DOI: 10.1016/j.talanta.2010.10.064.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Additional extraction description:
headspace solid-phase microextraction
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Substance:
Benzaldehyde (RF-00008323-PAR)
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Additional substance description:
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Analytical method code:
Gaschromatography (GC) (F037A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Benzaldehyde
Composition #7: Pereira, Joao., Pereira, Jorge., Camara, Jose S. Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile-Identification of novel compounds . talanta, 2011, vol. 83, no. 3, p. 899–906. DOI: 10.1016/j.talanta.2010.10.064.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Additional extraction description:
headspace solid-phase microextraction
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Substance:
Benzophenone derivatives (RF-00010824-PAR)
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Analytical method code:
Gaschromatography (GC) (F037A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Benzophenone (Pubchem reports adverse effects on reproduction)
Composition #8: Pereira, Joao., Pereira, Jorge., Camara, Jose S. Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile-Identification of novel compounds . talanta, 2011, vol. 83, no. 3, p. 899–906. DOI: 10.1016/j.talanta.2010.10.064.
[
DOI link]
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Additional extraction description:
headspace solid-phase microextraction
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Substance:
oxalic acid (RF-00000356-NTR)
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Additional substance description:
Ethanedioic acid
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Analytical method code:
Gaschromatography (GC) (F037A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Ethanedioic acid (oxalic acid)
Endpoint study
#1: Benalla, W., Bellahcen, S., Bnouham, M. Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors. current diabetes reviews, 2010, vol. 6, no. 4, p. 247–254. DOI: 10.2174/157339910791658826.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
methanol
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Type of toxicological test:
in vitro (CHD061TT)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
alpha-amylase-inhibiting activity
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-amylase-inhibiting activity
Endpoint study
#2: Benalla, W., Bellahcen, S., Bnouham, M. Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors. current diabetes reviews, 2010, vol. 6, no. 4, p. 247–254. DOI: 10.2174/157339910791658826.
[
DOI link]
-
Study relevance:
Human health
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Additional plant/substance description:
methanol
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Type of toxicological test:
in vitro (CHD061TT)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
alpha-glucosidase-inhibiting activity
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-glucosidase-inhibiting activity