EFSA
ecomole
vscht
  2. Rheum australe D. Don // Rheum emodi Wall. ex Meisn.

Rheum australe D. Don // Rheum emodi Wall. ex Meisn.

Family:
Polygonaceae
Approval state:
Approved
Number of articles retrieved:
251
Number of processed references:
6
Compositions
#1: 1,8-dihydroxyanthraquinone derivatives (10-Hydroxycascaroside C and D; rhein-11-O- β-D-glucoside, 6-methyl-rhein) #2: Furan derivatives (carpusin, maesopsin) #3: chrysophanol (RF-00003737-PAR) - natural #4: Aloe-emodin (RF-00003670-PAR) - natural #5: Emodin (RF-00003798-PAR)- natural #6: physcion (RF-00003993-PAR)- natural #7: p-coumaric acid (RF-00003532-PAR) #8: gallic acid (RF-00003821-PAR) #9: Aloe-emodin (RF-00003670-PAR) #10: Emodin (RF-00003798-PAR) #11: Emodin monomethylether (anthraquinone) #12: Anthraquinone glycosides #13: Chrysophanol #14: Phlobatannins #15: cardiac glycosides (cx000589)
Endpoint Studies
#1: alpha-glucosidase inhibition - emodin
Genotoxicity
Composition #1: Singh, P., Nee Pant, G.J., Rawat, M.S.M. Phytochemistry and biological activity perspectives of rheum species. Natural Products Journal, 2016, vol. 6, no. 2, p. 84–93. .
Composition #2: Singh, P., Nee Pant, G.J., Rawat, M.S.M. Phytochemistry and biological activity perspectives of rheum species. Natural Products Journal, 2016, vol. 6, no. 2, p. 84–93. .
Composition #3: Rokaya, Maan Bahadur., Marsik, Petr., Muenzbergova, Zuzana. Active constituents in Rheum acuminatum and Rheum australe (Polygonaceae) roots: A variation between cultivated and naturally growing plants. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2012, vol. 41, p. 83–90. DOI: 10.1016/j.bse.2011.11.004. [DOI link]
Composition #4: Rokaya, Maan Bahadur., Marsik, Petr., Muenzbergova, Zuzana. Active constituents in Rheum acuminatum and Rheum australe (Polygonaceae) roots: A variation between cultivated and naturally growing plants. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2012, vol. 41, p. 83–90. DOI: 10.1016/j.bse.2011.11.004. [DOI link]
Composition #5: Rokaya, Maan Bahadur., Marsik, Petr., Muenzbergova, Zuzana. Active constituents in Rheum acuminatum and Rheum australe (Polygonaceae) roots: A variation between cultivated and naturally growing plants. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2012, vol. 41, p. 83–90. DOI: 10.1016/j.bse.2011.11.004. [DOI link]
Composition #6: Rokaya, Maan Bahadur., Marsik, Petr., Muenzbergova, Zuzana. Active constituents in Rheum acuminatum and Rheum australe (Polygonaceae) roots: A variation between cultivated and naturally growing plants. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2012, vol. 41, p. 83–90. DOI: 10.1016/j.bse.2011.11.004. [DOI link]
Composition #7: Jahan, Nazish., Khalil-Ur-Rahman., Ali, Shoukat., Asi, M. Rafiq. PHENOLIC ACID AND FLAVONOL CONTENTS OF GEMMO-MODIFIED AND NATIVE EXTRACTS OF SOME INDIGENOUS MEDICINAL PLANTS. PAKISTAN JOURNAL OF BOTANY, 2013, vol. 45, no. 5, p. 1515–1519. .
Composition #8: Jahan, Nazish., Khalil-Ur-Rahman., Ali, Shoukat., Asi, M. Rafiq. PHENOLIC ACID AND FLAVONOL CONTENTS OF GEMMO-MODIFIED AND NATIVE EXTRACTS OF SOME INDIGENOUS MEDICINAL PLANTS. PAKISTAN JOURNAL OF BOTANY, 2013, vol. 45, no. 5, p. 1515–1519. .
Composition #9: Ye, Ben-Gui., Feng, Yong., Wang, Shu. Scientific evaluation of the acute toxicity and 13-week subchronic toxicity of Rheum emodi rhizome extracts in Sprague Dawley rats. FOOD AND CHEMICAL TOXICOLOGY, 2014, vol. 66, p. 278–285. DOI: 10.1016/j.fct.2014.01.051. [DOI link]
Composition #10: Ye, Ben-Gui., Feng, Yong., Wang, Shu. Scientific evaluation of the acute toxicity and 13-week subchronic toxicity of Rheum emodi rhizome extracts in Sprague Dawley rats. FOOD AND CHEMICAL TOXICOLOGY, 2014, vol. 66, p. 278–285. DOI: 10.1016/j.fct.2014.01.051. [DOI link]
Composition #11: Ye, Ben-Gui., Feng, Yong., Wang, Shu. Scientific evaluation of the acute toxicity and 13-week subchronic toxicity of Rheum emodi rhizome extracts in Sprague Dawley rats. FOOD AND CHEMICAL TOXICOLOGY, 2014, vol. 66, p. 278–285. DOI: 10.1016/j.fct.2014.01.051. [DOI link]
Composition #12: Ye, Ben-Gui., Feng, Yong., Wang, Shu. Scientific evaluation of the acute toxicity and 13-week subchronic toxicity of Rheum emodi rhizome extracts in Sprague Dawley rats. FOOD AND CHEMICAL TOXICOLOGY, 2014, vol. 66, p. 278–285. DOI: 10.1016/j.fct.2014.01.051. [DOI link]
Composition #13: Ye, Ben-Gui., Feng, Yong., Wang, Shu. Scientific evaluation of the acute toxicity and 13-week subchronic toxicity of Rheum emodi rhizome extracts in Sprague Dawley rats. FOOD AND CHEMICAL TOXICOLOGY, 2014, vol. 66, p. 278–285. DOI: 10.1016/j.fct.2014.01.051. [DOI link]
Composition #14: Kumar, Devanga Ragupathi Naveen., George, Vazhapilly Cijo., Suresh, Palamadai Krishnan., Kumar, Rangasamy Ashok. Cancer-specific chemoprevention and anti-metastatic potentials of Rheum emodi rhizome ethyl acetate extracts and identification of active principles through HPLC and GC-MS analysis. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, vol. 28, no. 1, p. 83–93. .
Composition #15: Kumar, Devanga Ragupathi Naveen., George, Vazhapilly Cijo., Suresh, Palamadai Krishnan., Kumar, Rangasamy Ashok. Cancer-specific chemoprevention and anti-metastatic potentials of Rheum emodi rhizome ethyl acetate extracts and identification of active principles through HPLC and GC-MS analysis. PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, vol. 28, no. 1, p. 83–93. .
Endpoint study #1: Arvindekar, Aditya., More, Tanaji., Payghan, Pavan V., Laddha, Kirti., Ghoshal, Nanda., Arvindekar, Akalpita. Evaluation of anti-diabetic and alpha glucosidase inhibitory action of anthraquinones from Rheum emodi. FOOD & FUNCTION, 2015, vol. 6, no. 8, p. 2693–2700. DOI: 10.1039/c5fo00519a. [DOI link]