EFSA Compendium of Botanicals

Draft - work in progress

Ziziphus xylopyrus (Retz.) Willd.

Family:: Rhamnaceae
Approval state:: Approved
Number of articles retrieved:: 34
Number of processed references:: 6

Compositions

#1: Alkaloids (cyclic peptide alkaloids, xylopyrine A and B #2: cyclic peptide alkaloids: xylopyrine D and E #3: cyclopeptide alkaloids: scutainine C, xylopyrine C #4: cyclopeptide alkaloids; nummularine P, sativanine H, xylopyrine F #5: cyclopeptide alkaloids: xylopyrine G and H #6: cardiac glycosides (aerial parts) #7: steroidal glycosides (aerial parts) #8: saponins (aerial parts) #9: alkaloids (aerial parts)

Endpoint Studies

Genotoxicity

Composition #1: Singh, Ashok Kumar., Pandey, Manoj Bhushan., Singh, Virendra Pratap., Pandey, Vidya Bhushan. Xylopyrine-A and xylopyrine-B, two new peptide alkaloids from Zizyphus xylopyra. Natural Product Research, 2007, p. 1114–1120. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

C6H6–NH4OH–MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Cyclic peptide alkaloids, xylopyrine A and B
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

melting point, optical rotations, IR, NMR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids (cyclic peptide alkaloids, xylopyrine A and B

Composition #2: Pandey, Manoj B., Singh, Ashok K., Singh, Jagdish P., Singh, Virendra P., Pandey, Vidya B. Three new cyclopeptide alkaloids from Zizyphus species. Journal of Asian Natural Products Research, 2008, p. 709–713. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

C6H6–NH4OH–MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

xylopyrine D and E
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

melting point, optical rotations, IR, NMR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cyclic peptide alkaloids: xylopyrine D and E

Composition #3: Singh, Ashok K., Pandey, Manoj B., Singh, Virendra P., Pandey, Vidya B. Xylopyrine-C, a new cyclopeptide alkaloid from Zizyphus xylopyra. Journal of Asian Natural Products Research, 2008, p. 715–718. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

C6H6–NH4OH–MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

cyclopeptide alkaloids: scutainine C, xylopyrine C
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

melting point, optical rotations, IR, NMR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cyclopeptide alkaloids: scutainine C, xylopyrine C

Composition #4: Pandey, Manoj B., Singh, Jagdish P., Singh, Ashok K., Singh, Virendra P. Xylopyrine-F, a new cyclopeptide alkaloid from Zizyphus xylopyra. Journal of Asian Natural Products Research, 2008, p. 725–728. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

C6H6–NH4OH–MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

cyclopeptide alkaloids (nummularine P, sativanine H, xylopyrine F)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

melting point, optical rotations, IR, NMR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cyclopeptide alkaloids; nummularine P, sativanine H, xylopyrine F

Composition #5: Pandey, Manoj B., Singh, Sarita., Malhotra, Meenakshi., Pandey, Vidya B., Singh, Tryambak D. Two new 14-membered cyclopeptide alkaloids from Zizyphus xylopyra. Natural Product Research, 2012, p. 836–841. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

C6H6–NH4OH–MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

cyclopeptide alkaloids: xylopyrine G and H
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

melting point, UV, IR, HRMS, NMR, TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cyclopeptide alkaloids: xylopyrine G and H

Composition #6: Gupta, Pradeep Kumar., Varshney, Dharmendra Kumar., Kumar, Umesh., Bhavna. Phytochemical studies of Ziziphus xylopyrus wild. Archives of Applied Science Research, 2013, p. 142–152. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardiac glycosides (aerial parts)

Composition #7: Gupta, Pradeep Kumar., Varshney, Dharmendra Kumar., Kumar, Umesh., Bhavna. Phytochemical studies of Ziziphus xylopyrus wild. Archives of Applied Science Research, 2013, p. 142–152. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

steroidal glycosides (RF-00011482-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steroidal glycosides (aerial parts)

Composition #8: Gupta, Pradeep Kumar., Varshney, Dharmendra Kumar., Kumar, Umesh., Bhavna. Phytochemical studies of Ziziphus xylopyrus wild. Archives of Applied Science Research, 2013, p. 142–152. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins (aerial parts)

Composition #9: Gupta, Pradeep Kumar., Varshney, Dharmendra Kumar., Kumar, Umesh., Bhavna. Phytochemical studies of Ziziphus xylopyrus wild. Archives of Applied Science Research, 2013, p. 142–152. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water, ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids (aerial parts)