EFSA Compendium of Botanicals

Draft - work in progress

Ziziphus oenoplia (L.) Mill.

Family:: Rhamnaceae
Approval state:: Approved
Number of articles retrieved:: 31
Number of processed references:: 2

Compositions

#1: Cyclic pentapetides (ziziphine-N, -O, -P, -Q) #2: saponins #3: alkaloids #4: tannins

Endpoint Studies

Genotoxicity

Composition #1: Suksamrarn, S., Suwannapoch, N., Aunchai, N., Kuno, M., Ratananukul, P., Haritakun, R., Jansakul, C., Ruchirawat, S. Ziziphine N, O, P and Q, new antiplasmodial cyclopeptide alkaloids from Ziziphus oenoplia var. brunoniana. TETRAHEDRON, 2005, vol. 61, no. 5, p. 1175–1180. DOI: 10.1016/j.tet.2004.11.053. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

hexane, EtOAc, MeOH
Substance:

Cyclic pentapeptides Cyclic pentapeptides (RF-00010842-PAR)
Additional substance description:

ziziphine-N, -O, P, Q
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cyclic pentapetides (ziziphine-N, -O, -P, -Q)

Composition #2: Rao, Ch V., Rawat, A. K. S., Singh, Anil P., Singh, Arpita., Verma, Neeraj. Hepatoprotective potential of ethanolic extract of Ziziphus oenoplia (L.) Mill roots against antitubercular drugs induced hepatotoxicity in experimental models. ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2012, vol. 5, no. 4, p. 283–288. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins

Composition #3: Rao, Ch V., Rawat, A. K. S., Singh, Anil P., Singh, Arpita., Verma, Neeraj. Hepatoprotective potential of ethanolic extract of Ziziphus oenoplia (L.) Mill roots against antitubercular drugs induced hepatotoxicity in experimental models. ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2012, vol. 5, no. 4, p. 283–288. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids

Composition #4: Rao, Ch V., Rawat, A. K. S., Singh, Anil P., Singh, Arpita., Verma, Neeraj. Hepatoprotective potential of ethanolic extract of Ziziphus oenoplia (L.) Mill roots against antitubercular drugs induced hepatotoxicity in experimental models. ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2012, vol. 5, no. 4, p. 283–288. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins