EFSA Compendium of Botanicals

Draft - work in progress

Wrightia tinctoria R.Br.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 273
Number of processed references:: 5

Compositions

#1: Tannins in leaves #2: Alkaloids in stem bark #3: Saponins in roots #4: Cardiac glycosides in leaves and roots #5: Alkaloids (tryptanthrin) in leaves #6: Alkaloids in bark #7: Alkaloids in seeds #8: Saponins in seeds #9: Tannins in seeds #10: Tryptanthrin ( alkaloid) in leaves #11: Trypthanhrin (aaloidd) in live plant

Endpoint Studies

Genotoxicity

Composition #1: Khyade, Mahendra S., Vaikos, Nityanand P. Wrightia tinctoria R. Br.(-)a review on its ethnobotany, pharmacognosy and pharmacological profile . journal of coastal life medicine, 2014, vol. 2, no. 10, p. 826–840. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in leaves

Composition #2: Khyade, Mahendra S., Vaikos, Nityanand P. Wrightia tinctoria R. Br.(-)a review on its ethnobotany, pharmacognosy and pharmacological profile . journal of coastal life medicine, 2014, vol. 2, no. 10, p. 826–840. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Additional extraction description:

stem bark; extract unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in stem bark

Composition #3: Khyade, Mahendra S., Vaikos, Nityanand P. Wrightia tinctoria R. Br.(-)a review on its ethnobotany, pharmacognosy and pharmacological profile . journal of coastal life medicine, 2014, vol. 2, no. 10, p. 826–840. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

Unspecified
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in roots

Composition #4: Khyade, Mahendra S., Vaikos, Nityanand P. Wrightia tinctoria R. Br.(-)a review on its ethnobotany, pharmacognosy and pharmacological profile . journal of coastal life medicine, 2014, vol. 2, no. 10, p. 826–840. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Additional extraction description:

unspecified
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardiac glycosides in leaves and roots

Composition #5: Khyade, Mahendra S., Vaikos, Nityanand P. Wrightia tinctoria R. Br.(-)a review on its ethnobotany, pharmacognosy and pharmacological profile . journal of coastal life medicine, 2014, vol. 2, no. 10, p. 826–840. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

tryptanthrin
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids (tryptanthrin) in leaves

Composition #6: Sethi, P. D. Separation of alkaloidal constituents of Wrightia tinctoria by TLC [thin-layer chromatography]. Planta Medica, 1969, p. 26–29. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in bark

Composition #7: Bigoniya, P., Singh, C.S., Shukla, A. Pharmacognostical and physicochemical standardization of ethnopharmacologically important seeds of Lepidium sativum Linn. and Wrightia tinctoria R. Br. indian journal of natural products and resources, 2011, vol. 2, no. 4, p. 464–471. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.17-0.29
Internal remarks:

Alkaloids in seeds

Composition #8: Bigoniya, P., Singh, C.S., Shukla, A. Pharmacognostical and physicochemical standardization of ethnopharmacologically important seeds of Lepidium sativum Linn. and Wrightia tinctoria R. Br. indian journal of natural products and resources, 2011, vol. 2, no. 4, p. 464–471. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water ; ether
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.96-2.96
Internal remarks:

Saponins in seeds

Composition #9: Bigoniya, P., Singh, C.S., Shukla, A. Pharmacognostical and physicochemical standardization of ethnopharmacologically important seeds of Lepidium sativum Linn. and Wrightia tinctoria R. Br. indian journal of natural products and resources, 2011, vol. 2, no. 4, p. 464–471. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in seeds

Composition #10: Muruganandam, AV., Jaiswal, AK., Ghosal, S., Bhattacharya, SK. Effect of Wrightia tinctoria on the brain monoamines and metabolites in rats . biogenic amines, 1998, vol. 14, no. 6, p. 655–665. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

tryptanthrin (RF-00003611-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.21
Internal remarks:

Tryptanthrin ( alkaloid) in leaves

Composition #11: Muruganandam, AV., Bhattacharya, SK., Ghosal, S. Indole and flavanoid constituents of Wrightia tinctoria, W-tomentosa and W-coccinea . indian journal of chemistry section b-organic chemistry including medicinal chemistry, 2000, vol. 39, no. 2, p. 125–131. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

tryptanthrin (RF-00003611-PAR)
Additional substance description:

alkaloid
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Trypthanhrin (aaloidd) in live plant