EFSA Compendium of Botanicals

Draft - work in progress

Trachelospermum jasminoides (Lindl.) Lem.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 131
Number of processed references:: 7

Compositions

#1: Indole alkaloids (voacangine-7-hydroxyindolenine, tabernaemontanine) (leaf, stem) #2: ibogaine (leaves and stem) #3: Vobasine (leaf, stem) #4: Scopoletin #5: Triterpene saponins #6: Lignans (14 different, quantified; leaves and stem) #7: Lignans (trachelogenin, tracheloside) (stem) #8: Salicylic acid (leaves, stem) #9: Indole alkaloids (apparacine, conofiorine, coronaridine, voacangine, 19-epi-voacangarine) (leaves, stem)

Endpoint Studies

Genotoxicity

Composition #1: Atta-ur-Rahman., Fatima, T., Crank, George., Wasti, Shaheen. Alkaloids from Trachelospermum jasminoides. Planta Medica, 1988 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

indole alkaloids (RF-00004503-PAR)
Additional substance description:

voacangine-7-hydroxyindolenine, tabernaemontanine
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Indole alkaloids (voacangine-7-hydroxyindolenine, tabernaemontanine) (leaf, stem)

Composition #2: Atta-ur-Rahman., Fatima, T., Crank, George., Wasti, Shaheen. Alkaloids from Trachelospermum jasminoides. Planta Medica, 1988 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

ibogaine (RF-00003873-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

ibogaine (leaves and stem)

Composition #3: Atta-ur-Rahman., Fatima, T., Crank, George., Wasti, Shaheen. Alkaloids from Trachelospermum jasminoides. Planta Medica, 1988 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

vobasine (RF-00003634-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Vobasine (leaf, stem)

Composition #4: Yuan, Shanqin., Yu, Nengjiang., Zhao, Yimin., Xu, Bin., Yao, Zhiwei. Chemical constituents from Trachelosperomum jasminoides. zhongcaoyao, 2010, p. 179–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

Unspecified
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scopoletin

Composition #5: Tan, Xing-qi., Guo, Liang-jun., Kong, Fei-fei., Lv, Gui-yuan., Chen, Su-hong., Zhang, Li-dan., Zhou, Gui-fen., Zhang, Yue-wen., Fang, Hui. Studies on the anti-fatigue effect of the total triterpenoid saponins of Trachelospermi Caulis et folium. jiefangjun yaoxue xuebao, 2011, p. 128–131. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Triterpene saponins

Composition #6: Liu, Xiao-Ting., Wang, Xu-Guang., Yang, Yu., Xu, Rui., Meng, Fan-Hua., Yu, Neng-Jiang., Zhao, Yi-Min. Qualitative and quantitative analysis of lignan constituents in Caulis Trachelospermi by HPLC-QTOF-MS and HPLC-UV. Molecules, 2015, p. 8107–8124. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH resp. EtOH
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

14 different dibenzbutyrolactone lignans mean 28.5 mg/g. Of this mainly tracheloside mean 7.2 mg/g.
Analytical method code:

LC-QTOF-MS (F337A)
Analytical method - additional description:

HPLC-UV
Result unit:

Milligram/gram (G060A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.4-37.9
Internal remarks:

Lignans (14 different, quantified; leaves and stem)

Composition #7: Li, L., Meng, F., Guo, J., Sun, L., Yu, N., Zhao, Y. Simultaneous quantification of tracheloside and trachelogenin in rat plasma using liquid chromatography/tandem mass spectrometry. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2011, vol. 879, no. 15-16, p. 1033–1037. DOI: 10.1016/j.jchromb.2011.02.021. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

trachelogenin, tracheloside
Analytical method code:

LC-MS (F026A)
Analytical method - additional description:

NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans (trachelogenin, tracheloside) (stem)

Composition #8: Tan, XQ., Guo, LJ., Qiu, YH., Chen, HS., Tan, CH. Chemical constituents of Trachelospermum jasminoides. NATURAL PRODUCT RESEARCH, 2010, vol. 24, no. 13, p. 1248–1252. DOI: 10.1080/14786410903244962. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Salicylic acid (RF-00000241-VET)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Salicylic acid (leaves, stem)

Composition #9: ATTAURRAHMAN., FATIMA, T., MEHRUNNISA., IJAZ, S., CRANK, G., WASTI, S. INDOLE ALKALOIDS FROM TRACHELOSPERMUM-JASMINOIDES. PLANTA MEDICA, 1987, no. 1, p. 57–59. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

indole alkaloids (RF-00004503-PAR)
Additional substance description:

Apparicine, conofiorine, coronaridine, voacangine, 19-epi-voacangarine
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Indole alkaloids (apparacine, conofiorine, coronaridine, voacangine, 19-epi-voacangarine) (leaves, stem)