Draft - work in progress
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- Toddalia asiatica (L.) Lam. // Paullinia asiatica L.
Toddalia asiatica (L.) Lam. // Paullinia asiatica L.
- Family:
- Rutaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 268
- Number of processed references:
- 12
Compositions
#1: chelerythrine (bark)
#2: Alkaloids (leaf)
#3: Coumarins (leaf)
#4: tannins (leaf)
#5: Coumarins (toddaculine, mexeticin; stem)
#6: Chelerythrine (stem)
#7: Tannins (fruit, quantified)
#8: Saponins (fruit, quantified)
#9: Phytate (fruit, quantified)
#10: Oxalate (fruit, quantified)
#11: Coumarins (13, root bark)
#12: Alkaloids (9, root bark)
#13: Tannins (whole plant)
#14: Alkaloids (whole plant)
#15: Alkaloids (wood)
#16: Coumarins (wood)
#17: Coumarins (twigs, 7-geranyloxy-5-methoxycoumarin, 8-Geranyloxy-5,7-dimethoxycoumarin)
#18: Pimpinellin (root bark, quantified)
#19: Phellopterin (root bark, quantified)
#20: Isopimpinellin (root bark, quantified)
#21: phellopterin (root, quantified)
#22: isopimpinellin (root, quantified)
#23: pimpinellin (root, quantified)
#24: Alkaloids (e.g. toddaquinoline, root bark)
#25: Coumarins (root bark)
#26: Comuarins (root, toddasiatin)
#27: Alkaloids (root)
Composition #1: Yang, Liang., Guo, Jing., Fan, Baocheng. Fingerprint chromatography of cortex toddalia by HPLC. zhongguo yaoye, 2011, p. 21–22. .
-
-
Plant part:
Bark (as part-nature) (A066X)
-
Substance:
chelerythrine (RF-00004204-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
chelerythrine (bark)
Composition #2: Patil, Arun V., Jadhav, Varsha D., Patil, Poonam C. Ethnomedicinal and pharmacognostical studies on leaves of Toddalia asiatica L. Pharmacia Sinica, 2013, p. 76–80. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol, petroleum ether or ethanol
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids (leaf)
Composition #3: Patil, Arun V., Jadhav, Varsha D., Patil, Poonam C. Ethnomedicinal and pharmacognostical studies on leaves of Toddalia asiatica L. Pharmacia Sinica, 2013, p. 76–80. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol, petroleum ether, acetone or ethanol
-
Substance:
coumarins (RF-00004351-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (leaf)
Composition #4: Patil, Arun V., Jadhav, Varsha D., Patil, Poonam C. Ethnomedicinal and pharmacognostical studies on leaves of Toddalia asiatica L. Pharmacia Sinica, 2013, p. 76–80. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
chloroform
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannins (leaf)
Composition #5: Chen, Xiaoxue., Reheman, Simayi., Long, Shengjing. Studies on chemical constituents of Toddalia asiatica stems. xibei yaoxue zazhi, 2013, p. 337–339. .
-
-
Plant part:
Stem / stalk (as part-nature) (A067S)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethylacetate fraction
-
Substance:
coumarins (RF-00004351-PAR)
-
Additional substance description:
toddaculine, mexeticin
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Analytical method - additional description:
hplc, chemical methods
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (toddaculine, mexeticin; stem)
Composition #6: Chen, Xiaoxue., Reheman, Simayi., Long, Shengjing. Studies on chemical constituents of Toddalia asiatica stems. xibei yaoxue zazhi, 2013, p. 337–339. .
-
-
Plant part:
Stem / stalk (as part-nature) (A067S)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethylacetate fraction
-
Substance:
chelerythrine (RF-00004204-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Analytical method - additional description:
hplc, chemical methods
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Chelerythrine (stem)
Composition #7: Rout, Pramodini., Basak, Uday Chand. Evaluation of antinutritional factors in sixteen wild edible fruits of Odisha, India. International Journal of Current Science, 2014, p. 34–42. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
Liquid chromatography
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
64
-
Internal remarks:
Tannins (fruit, quantified)
Composition #8: Rout, Pramodini., Basak, Uday Chand. Evaluation of antinutritional factors in sixteen wild edible fruits of Odisha, India. International Journal of Current Science, 2014, p. 34–42. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
Liquid chromatography
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
140
-
Internal remarks:
Saponins (fruit, quantified)
Composition #9: Rout, Pramodini., Basak, Uday Chand. Evaluation of antinutritional factors in sixteen wild edible fruits of Odisha, India. International Journal of Current Science, 2014, p. 34–42. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
phytic acid (RF-00000363-NTR)
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
Liquid chromatography
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
9.2-9.8
-
Internal remarks:
Phytate (fruit, quantified)
Composition #10: Rout, Pramodini., Basak, Uday Chand. Evaluation of antinutritional factors in sixteen wild edible fruits of Odisha, India. International Journal of Current Science, 2014, p. 34–42. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
Oxalates (RF-00004308-PAR)
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
Liquid chromatography
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.5-4.7
-
Internal remarks:
Oxalate (fruit, quantified)
Composition #11: Tsai, I.-L., Chang, R.-G., Fang, S.-C., Ishikawa, T., Chen, I.-S. Chemical constituents from the root bark of Formosan Toddalia asiatica. chinese pharmaceutical journal, 1996, vol. 48, no. 1, p. 63–75. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Additional extraction description:
root bark
-
Substance:
coumarins (RF-00004351-PAR)
-
Additional substance description:
e.g toddaculin;5,7,8- trimethoxycoumarin;5-methoxy-suberenon,toddanol;6-(2- hydroxy-3-methoxy-3-methylbutyl)-5,7-dimethoxycoumarin;phellopterin;isopimpinellin;toddalolactone;toddasin, 8-hydroxy-5-methoxy psoralen;alloisoimperatorin
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
spectrometric methods
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (13, root bark)
Composition #12: Tsai, I.-L., Chang, R.-G., Fang, S.-C., Ishikawa, T., Chen, I.-S. Chemical constituents from the root bark of Formosan Toddalia asiatica. chinese pharmaceutical journal, 1996, vol. 48, no. 1, p. 63–75. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Additional extraction description:
roott bark
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Additional substance description:
norchelerythrine, bocconoline, arnottianamide, oxyavicine, γ-fagarine, oxychelerythrine, skimmianine, toddaquinoline and 4-methoxy-1-methyl-2-quinolone
-
Analytical method code:
Traditional analytical techniques (wet chemical tests) (F003A)
-
Analytical method - additional description:
spectrometric methods
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids (9, root bark)
Composition #13: Suresh B., Dhanasekaran S., Elango K., Sethuraman M., Rajan S. Anti-pyretic activity of some plants in female albino rats: a preliminary report. ancient science of life, 1995, p. 253–257. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Tannins (whole plant)
Composition #14: Suresh B., Dhanasekaran S., Elango K., Sethuraman M., Rajan S. Anti-pyretic activity of some plants in female albino rats: a preliminary report. ancient science of life, 1995, p. 253–257. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids (whole plant)
Composition #15: Tsai, IL., Wun, MF., Teng, CM., Ishikawa, T., Chen, IS. Anti-platelet aggregation constituents from formosan Toddalia asiatica. phytochemistry, 1998, vol. 48, no. 8, p. 1377–1382. DOI: 10.1016/S0031-9422(97)00678-X.
[
DOI link]
-
-
Plant part:
Wood (as part-nature) (A166P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids (wood)
Composition #16: Tsai, IL., Wun, MF., Teng, CM., Ishikawa, T., Chen, IS. Anti-platelet aggregation constituents from formosan Toddalia asiatica. phytochemistry, 1998, vol. 48, no. 8, p. 1377–1382. DOI: 10.1016/S0031-9422(97)00678-X.
[
DOI link]
-
-
Plant part:
Wood (as part-nature) (A166P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH
-
Substance:
coumarins (RF-00004351-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (wood)
Composition #17: Wang, F., Xu, Y., Liu, JK. New geranyloxycoumarins from Toddalia asiatica. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, vol. 11, no. 8, p. 752–756. DOI: 10.1080/10286020903048975.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Ethanol
-
Substance:
coumarins (RF-00004351-PAR)
-
Additional substance description:
7-geranyloxy-5-methoxycoumarin; 8-Geranyloxy-5,7-dimethoxycoumarin
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Analytical method - additional description:
UV, IR, NMR
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (twigs, 7-geranyloxy-5-methoxycoumarin, 8-Geranyloxy-5,7-dimethoxycoumarin)
Composition #18: Liu, Zhigang., Jiang, Minyan., Lu, Xiumei., Qin, Feng., Song, Yang., Wen, Jing., Li, Famei. Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2012, vol. 891, p. 102–108. DOI: 10.1016/j.jchromb.2012.02.022.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
75% EtOH, root bark
-
Substance:
pimpinellin (RF-00003997-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Result unit:
Milligram/millilitre (G191A)
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
10.1
-
Internal remarks:
Pimpinellin (root bark, quantified)
Composition #19: Liu, Zhigang., Jiang, Minyan., Lu, Xiumei., Qin, Feng., Song, Yang., Wen, Jing., Li, Famei. Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2012, vol. 891, p. 102–108. DOI: 10.1016/j.jchromb.2012.02.022.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
75% EtOH, root bark
-
Substance:
Phellopterin (RF-00003560-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Result unit:
Milligram/millilitre (G191A)
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
5.0
-
Internal remarks:
Phellopterin (root bark, quantified)
Composition #20: Liu, Zhigang., Jiang, Minyan., Lu, Xiumei., Qin, Feng., Song, Yang., Wen, Jing., Li, Famei. Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2012, vol. 891, p. 102–108. DOI: 10.1016/j.jchromb.2012.02.022.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
75% EtOH, root bark
-
Substance:
Isopimpinellin (RF-00003784-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Result unit:
Milligram/millilitre (G191A)
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
3.9
-
Internal remarks:
Isopimpinellin (root bark, quantified)
Composition #21: Qiu, HY., Xiao, XH., Li, GK. Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography. JOURNAL OF SEPARATION SCIENCE, 2012, vol. 35, no. 7, p. 901–906. DOI: 10.1002/jssc.201100995.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Phellopterin (RF-00003560-PAR)
-
Analytical method code:
UHPLC-MS-MS (F608A)
-
Analytical method - additional description:
NMR
-
Result unit:
Milligram/gram (G060A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.95
-
Internal remarks:
phellopterin (root, quantified)
Composition #22: Qiu, HY., Xiao, XH., Li, GK. Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography. JOURNAL OF SEPARATION SCIENCE, 2012, vol. 35, no. 7, p. 901–906. DOI: 10.1002/jssc.201100995.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Isopimpinellin (RF-00003784-PAR)
-
Analytical method code:
UHPLC-MS-MS (F608A)
-
Analytical method - additional description:
NMR
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.85
-
Internal remarks:
isopimpinellin (root, quantified)
Composition #23: Qiu, HY., Xiao, XH., Li, GK. Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography. JOURNAL OF SEPARATION SCIENCE, 2012, vol. 35, no. 7, p. 901–906. DOI: 10.1002/jssc.201100995.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
pimpinellin (RF-00003997-PAR)
-
Analytical method code:
UHPLC-MS-MS (F608A)
-
Analytical method - additional description:
NMR
-
Result unit:
Milligram/gram (G060A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
2.55
-
Internal remarks:
pimpinellin (root, quantified)
Composition #24: CHEN, IS., TSAI, IL., WU, SJ., SHEEN, WS., ISHIKAWA, T., ISHII, H. TODDAQUINOLINE FROM FORMOSAN TODDALIA-ASIATICA. PHYTOCHEMISTRY, 1993, vol. 34, no. 5, p. 1449–1451. DOI: 10.1016/0031-9422(91)80052-3.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Additional substance description:
e.g. toddaquinoline
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids (e.g. toddaquinoline, root bark)
Composition #25: CHEN, IS., TSAI, IL., WU, SJ., SHEEN, WS., ISHIKAWA, T., ISHII, H. TODDAQUINOLINE FROM FORMOSAN TODDALIA-ASIATICA. PHYTOCHEMISTRY, 1993, vol. 34, no. 5, p. 1449–1451. DOI: 10.1016/0031-9422(91)80052-3.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
coumarins (RF-00004351-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Coumarins (root bark)
Composition #26: Tsai, IL., Fang, SC., Ishikawa, T., Chang, CT., Chen, IS. N-cyclohexyl amides and a dimeric coumarin from formosan Toddalia asiatica. PHYTOCHEMISTRY, 1997, vol. 44, no. 7, p. 1383–1386. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
coumarins (RF-00004351-PAR)
-
Additional substance description:
toddasiatin
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Analytical method - additional description:
IR, C and H NMR, UV
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Comuarins (root, toddasiatin)
Composition #27: Tsai, IL., Fang, SC., Ishikawa, T., Chang, CT., Chen, IS. N-cyclohexyl amides and a dimeric coumarin from formosan Toddalia asiatica. PHYTOCHEMISTRY, 1997, vol. 44, no. 7, p. 1383–1386. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Additional substance description:
e.g
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Analytical method - additional description:
IR, C and H NMR, UV
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Alkaloids (root)
Endpoint study
#1: Suresh B., Dhanasekaran S., Elango K., Sethuraman M., Rajan S. Anti-pyretic activity of some plants in female albino rats: a preliminary report. ancient science of life, 1995, p. 253–257. .
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Study relevance:
Human health
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Plant part:
Live plants (as part-nature) (A0BA0)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
ethanol
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Type of toxicological test:
acute toxicity (CHD016TT)
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Limit test:
Not applicable
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Tested organism:
Rat (as animal) (A0CNV)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
20
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Endpoint measured:
Lethal dose rate in 50% of experimental organisms (CHD029EP)
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Concentration unit:
Milligrams per kilogram body weight (G225A)
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Effect concentration:
350
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Critical effect:
Other toxicities (TOX19A)
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
LD50 rat