EFSA Compendium of Botanicals

Draft - work in progress

Teucrium scordium L.

Family:: Lamiaceae
Approval state:: Approved
Number of articles retrieved:: 56
Number of processed references:: 4

Compositions

#1: clerodane diterpenes #2: 6-acetylteucjaponin B (clerodane diterpene) #3: Pulegone #4: 1,8-Cineole #5: Menthofuran #6: 6 alpha-hydroxyteuscordin (clerodane diterpene) #7: teucrin E (clerodane diterpene) #8: 6-ketoteuscordin (clerodane diterpene) #9: 2 beta, 6 beta-dihydroxyteuscordin (clerodane diterpene) #10: 6beta-hydroxyteuscordin (clerodane diterpene) #11: teuscordinon (clerodane diterpene) #12: teucrin H4 (clerodane diterpene) #13: 2-keto-19-hydroxyteuscordin (clerodane diterpene)

Endpoint Studies

Genotoxicity

Composition #1: Papanov, G., Malakov, P. 6β-Hydroxyteuscordin and 2β-,6β-dihydroxyteuscordin. Two new diterpenoids from Teucrium scordium L. Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1982, p. 519–520. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

hydroxyteuscordin derivatives, teuscordinon, 6-ketoteuscordin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

clerodane diterpenes

Composition #2: Coll, J., Tandron, Y. Neo-clerodane diterpenes from Teucrium fruticans. PHYTOCHEMISTRY, 2004, vol. 65, no. 4, p. 387–392. DOI: 10.1016/j.phytochem.2003.09.018. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

6-acetylteucjaponin B
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

6-acetylteucjaponin B (clerodane diterpene)

Composition #3: Sharififar, Fraiba., Mandavi, Zahra., Mirtajaldini, Mansour., Purhematy, Amin. Volatile Constituents of Aerial Parts of Teucrium scordium L. From Iran. journal of essential oil research, 2010, vol. 22, no. 3, p. 202–204. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(+)-pulegone (RF-00003398-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

39.1
Internal remarks:

Pulegone

Composition #4: Sharififar, Fraiba., Mandavi, Zahra., Mirtajaldini, Mansour., Purhematy, Amin. Volatile Constituents of Aerial Parts of Teucrium scordium L. From Iran. journal of essential oil research, 2010, vol. 22, no. 3, p. 202–204. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.1
Internal remarks:

1,8-Cineole

Composition #5: Sharififar, Fraiba., Mandavi, Zahra., Mirtajaldini, Mansour., Purhematy, Amin. Volatile Constituents of Aerial Parts of Teucrium scordium L. From Iran. journal of essential oil research, 2010, vol. 22, no. 3, p. 202–204. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

menthofuran (RF-00003924-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.2
Internal remarks:

Menthofuran

Composition #6: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

6 alpha-hydroxyteuscordin (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

6 alpha-hydroxyteuscordin (clerodane diterpene)

Composition #7: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

teucrin E (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

teucrin E (clerodane diterpene)

Composition #8: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

6-ketoteuscordin (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

6-ketoteuscordin (clerodane diterpene)

Composition #9: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

2 beta, 6 beta-dihydroxyteuscordin (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

2 beta, 6 beta-dihydroxyteuscordin (clerodane diterpene)

Composition #10: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

6beta-hydroxyteuscordin (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

6beta-hydroxyteuscordin (clerodane diterpene)

Composition #11: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

teuscordinon (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

teuscordinon (clerodane diterpene)

Composition #12: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

teucrin H4 (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

teucrin H4 (clerodane diterpene)

Composition #13: PAPANOV, GY., MALAKOV, PY. 2-KETO-19-HYDROXYTEUSCORDIN, A NEO-CLERODANE DITERPENE FROM TEUCRIUM-SCORDIUM. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

2-keto-19-hydroxyteuscordin (clerodane diterpene)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

2-keto-19-hydroxyteuscordin (clerodane diterpene)