Endpoint study
#1: 최혜정., Choi, Youngwhan., 정영기., Kang, Jumsoon., Joo, Woo Hong. Inhibitory Activity on the Diabetes Related Enzymes of Tetragonia tetragonioides . korean society for biotechnology and bioengineering journal, 2008, vol. 23, no. 5, p. 419–424. .
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Study relevance:
Human health
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Plant part:
Unspecified (A07XD)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
hexane
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Enzyme inhibition (CHD067EP)
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Concentration unit:
Milligram/millilitre (G191A)
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Effect concentration:
2.043
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Target tissue:
digestive: Pancreas (TT024A)
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Effect description:
inhibits more than 50% of pancreatin α-amylase activity
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-amylase inhibition
Endpoint study
#2: 최혜정., Choi, Youngwhan., 정영기., Kang, Jumsoon., Joo, Woo Hong. Inhibitory Activity on the Diabetes Related Enzymes of Tetragonia tetragonioides . korean society for biotechnology and bioengineering journal, 2008, vol. 23, no. 5, p. 419–424. .
-
Study relevance:
Human health
-
Plant part:
Unspecified (A07XD)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Additional plant/substance description:
hexane
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Half maximal inhibitory concentration (CHD021EP)
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Concentration unit:
Milligram/millilitre (G191A)
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Effect concentration:
0.723
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Target tissue:
digestive: Pancreas (TT024A)
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Effect description:
Inhibitory activity on yeast α-glucosidase
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-glucosidase inhibition
