EFSA Compendium of Botanicals

Draft - work in progress

Tecoma stans (L.) Juss. ex Kunth

Family:: Bignoniaceae
Approval state:: Approved
Number of articles retrieved:: 386
Number of processed references:: 6

Compositions

#1: tannins #2: cardiac glycosides #3: saponins #4: Tecostanine, Tecostidine #5: tecomanine in whole plant #6: N-Norskytanthine, 4-Noractinidine, Boschniakine in leaves #7: tannins #8: monoterpene alkaloids in fruits #9: monoterpene alkaloids in fruits

Endpoint Studies

#1: reduces male fertility

Genotoxicity

Composition #1: Sanchez-Arreola, E., Maiti, R. K., Fernnandez, L. R. Tecanhuey., Espino, Gudelia Martinez. Traditional uses and a preliminary study on the phytochemistry of nine medicinal plant species of common use in high land of Puebla and Tlaxcala, Mexico . crop research (hisar), 2005, vol. 30, no. 1, p. 113–118. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #2: Sanchez-Arreola, E., Maiti, R. K., Fernnandez, L. R. Tecanhuey., Espino, Gudelia Martinez. Traditional uses and a preliminary study on the phytochemistry of nine medicinal plant species of common use in high land of Puebla and Tlaxcala, Mexico . crop research (hisar), 2005, vol. 30, no. 1, p. 113–118. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardiac glycosides

Composition #3: Sanchez-Arreola, E., Maiti, R. K., Fernnandez, L. R. Tecanhuey., Espino, Gudelia Martinez. Traditional uses and a preliminary study on the phytochemistry of nine medicinal plant species of common use in high land of Puebla and Tlaxcala, Mexico . crop research (hisar), 2005, vol. 30, no. 1, p. 113–118. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins

Composition #4: Dickinson, E. M., Jones, Gurnos. Pyrindan alkaloids from Tecoma stans. tetrahedron, 1969, p. 1523–1529. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol or methanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Pyrindane alkaloids: Tecostanine, Tecostidine
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tecostanine, Tecostidine

Composition #5: Dickinson, E. M., Jones, Gurnos. Pyrindan alkaloids from Tecoma stans. tetrahedron, 1969, p. 1523–1529. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol or methanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Tecomanine (pyrindane alkaloids)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tecomanine in whole plant

Composition #6: Dickinson, E. M., Jones, Gurnos. Pyrindan alkaloids from Tecoma stans. tetrahedron, 1969, p. 1523–1529. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol or methanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Pyrindane alkaloids: N-Norskytanthine, 4-Noractinidine, Boschniakine
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

N-Norskytanthine, 4-Noractinidine, Boschniakine in leaves

Composition #7: Castaneda Sortibran, America., Tellez, Maria Guadalupe Ordaz., Ocotero, Veronica Munoz., Carballo-Ontiveros, Marco Antonio., Garcia, Angelica Mendez., Valdes, Rocio Jimena Jimenez., Gutierrez, Elizabeth Romero., Rodriguez-Arnaiz, Rosario. Chronic toxicity, genotoxic assay, and phytochemical analysis of four traditional medicinal plants. . journal of medicinal food, 2011, vol. 14, no. 9, p. 1018–22. DOI: 10.1089/jmf.2010.0178. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #8: Marzouk, Mohamed S. A., Gamal-Eldeen, Amira M., Mohamed, Mona A., El-Sayed, Mortada M. Antioxidant and anti-proliferative active constituents of Tecoma stans against tumor cell lines . natural product communications, 2006, vol. 1, no. 9, p. 735–743. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 80%
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

monoterpene alkaloid, 5-hydroxy-skytanthine hydrochloride
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

monoterpene alkaloids in fruits

Composition #9: LINS, AP., FELICIO, JD. MONOTERPENE ALKALOIDS FROM TECOMA-STANS. PHYTOCHEMISTRY, 1993, vol. 34, no. 3, p. 876–878. DOI: 10.1016/0031-9422(93)85381-Z. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

monoterpene alkaloids: 7-hydroxyskytanthine, 4-hydroxytecomanine, 5-hydroxyskytanthine and tecomanine
Analytical method code:

Phytochemical screening (F604A)
Analytical method - additional description:

2D NMR, C NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

monoterpene alkaloids in fruits

Endpoint study #1: Mathur, Nidhi., Jain, G. C., Pandey, Geeta. Effect of Tecoma stans Leaves on the Reproductive System of Male Albino Rats . international journal of pharmacology, 2010, vol. 6, no. 2, p. 152–156. .

Study relevance:

Human health
Plant part:

Leaves (as part-nature) (A0EKT)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

ethanol 50%
Type of toxicological test:

reproduction toxicity (CHD009TT)
Tested organism:

Rat (as animal) (A0CNV)
Strain of test organism:

Wistar (CHD013ST)
Sex:

Male
Route of exposure:

ORAL: GAVAGE (OECD2231PL)
Exposure duration:

60.0
Unit of exposure duration:

Day (G134A)
Number of organisms dosed:

6
Control groups used:

yes
Endpoint measured:

Concentration producing lethality in 10% of experimental organisms (CHD022EP)
Concentration unit:

Milligrams per kilogram body weight per day (G211A)
Effect concentration:

500
Critical effect:

REPRODUCTIVE (TOX05A)
Target tissue:

urogenital: Testes (TT050A)
Effect description:

decline in serum testosterone levels, reduced sperm count and motility in cauda epididymis
Effect or parameter linked to the endpoint:

reproduction (CHD014BE)
Internal remarks:

reduces male fertility