EFSA Compendium of Botanicals

Draft - work in progress

Styrax officinalis L.

Family:: Styracaceae
Approval state:: Approved
Number of articles retrieved:: 88
Number of processed references:: 6

Compositions

#1: steroidal saponin #2: styraxin #3: triterpene saponins #4: benzofurans in seeds #5: eugenol in essential oil from stems #6: Americanin A

Endpoint Studies

Genotoxicity

Composition #1: Segal, R. A new type of saponin from Styrax officinalis. Harokeach Haivri, 1964, p. 104–105. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

Unspecified
Substance:

steroidal saponins (RF-00010818-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steroidal saponin

Composition #2: Ulubelen, A., Saiki, Y., Lotter, H., Chari, V. M., Wagner, H. Chemical components of Styrax officinalis L. IV. The structure of a new lignan styraxin. planta medica, 1978, p. 403–407. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

wather ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

styraxin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

styraxin

Composition #3: Yayla, Y., Alankus-Caliskan, O., Anil, H., Bates, RB., Stessman, CC., Kane, VV. Saponins from Styrax officinalis. FITOTERAPIA, 2002, vol. 73, no. 4, p. 320–326. DOI: 10.1016/S0367-326X(02)00086-2. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH(80%)
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Additional substance description:

Styrax saponin A-C, deacylsaponin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

triterpene saponins

Composition #4: Akgul, YY., Anil, H. Benzofurans and another constituent from seeds of Styrax officinalis. PHYTOCHEMISTRY, 2003, vol. 63, no. 8, p. 939–943. DOI: 10.1016/S0031-9422(03)00357-1. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Benzofurans (RF-00010791-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

benzofurans in seeds

Composition #5: Tayoub, Ghaleb., Schwob, Isabelle., Bessiere, Jean-Marie., Rabier, Jacques., Masotti, Veronique., Mevy, Jean-Philippe., Ruzzier, Martine., Girard, Gabriel., Viano, Josette. Essential oil composition of leaf, flower and stem of Styrax (Styrax officinalis L.) from south-eastern France . flavour and fragrance journal, 2006, vol. 21, no. 5, p. 809–812. DOI: 10.1002/ffj.1731. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.9
Internal remarks:

eugenol in essential oil from stems

Composition #6: Pazar, Erdinc., Akgul, Yurdanur. Chemical composition of the endocarps of fruits of Styrax officinalis L.. NATURAL PRODUCT RESEARCH, 2015, vol. 29, no. 15, p. 1466–1468. DOI: 10.1080/14786419.2014.1003063. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Additional extraction description:

Unspecified
Substance:

isoamericanin A (RF-00003876-PAR)
Additional substance description:

Americanin A
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

1H, 13C, COSY, NOESY, HMBC, HMQC and HR-ESI-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Americanin A