EFSA Compendium of Botanicals

Draft - work in progress

Strophanthus boivinii Baill.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 5
Number of processed references:: 4

Compositions

#1: strospeside #2: strospeside #3: paulioside #4: stroboside #5: paulioside #6: stroboside #7: boivinide A - roots #8: boivinide A - bark #9: boivinide B - wood #10: boivinide B - roots #11: boivinide B - bark #12: boivinide A - wood #13: boivinide C - wood #14: boivinide C - root #15: boivinide C - bark #16: boivinide E - wood #17: boivinide D - wood #18: boivinide D - bark #19: boivinide D - root #20: boivinide E - root #21: boivinide E - bark #22: boivinide F - root #23: boivinide F - bark #24: boivinide F - wood #25: 5a-corotoxigenin 3-O- β-D-boivinoside - wood #26: 5a-corotoxigenin 3-O- β-D-boivinoside - root #27: 5a-corotoxigenin 3-O- β-D-boivinoside - bark #28: uzarigenin 3-O- α-L-rhamnoside - root #29: uzarigenin 3-O- α-L-rhamnoside - wood #30: uzarigenin 3-O- α-L-rhamnoside - bark

Endpoint Studies

Genotoxicity

Composition #1: Schindler, O., Reichstein, T. XCIII. Identification of substance no. 763 from Strophanthus speciosus and S. boivinii as strospeside (desglucodigitalinum verum). Helvetica Chimica Acta, 1952, p. 442–446. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Fermentation (A0CQZ)
Substance:

strospeside (RF-00004066-PAR)
Additional substance description:

Gitoxigenin-3-beta-D-digitalopyranosid
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

strospeside

Composition #2: Schindler, O., Reichstein, T. Glycosides and aglycons. XCIV. Glycosides of the seeds of Strophanthus boivinii. Helvetica Chimica Acta, 1952, p. 673–686. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Fermentation (A0CQZ)
Additional extraction description:

water
Substance:

strospeside (RF-00004066-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

strospeside

Composition #3: Schindler, O., Reichstein, T. Glycosides and aglycons. XCIV. Glycosides of the seeds of Strophanthus boivinii. Helvetica Chimica Acta, 1952, p. 673–686. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Fermentation (A0CQZ)
Additional extraction description:

water
Substance:

Paulioside (RF-00011274-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

paulioside

Composition #4: Schindler, O., Reichstein, T. Glycosides and aglycons. XCIV. Glycosides of the seeds of Strophanthus boivinii. Helvetica Chimica Acta, 1952, p. 673–686. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Fermentation (A0CQZ)
Additional extraction description:

water
Substance:

Stroboside (RF-00011272-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

stroboside

Composition #5: Schindler, O., Reichstein, T. Glycosides and aglycons. XCVI. Milloside, paulioside, stroboside and boistroside. The glycosides from Strophanthus boivinii Baill. 2. Helvetica Chimica Acta, 1952, p. 730–745. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Paulioside (RF-00011274-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

paulioside

Composition #6: Schindler, O., Reichstein, T. Glycosides and aglycons. XCVI. Milloside, paulioside, stroboside and boistroside. The glycosides from Strophanthus boivinii Baill. 2. Helvetica Chimica Acta, 1952, p. 730–745. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Stroboside (RF-00011272-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

stroboside

Composition #7: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide A (RF-00011140-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide A - roots

Composition #8: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide A (RF-00011140-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide A - bark

Composition #9: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide B (RF-00011139-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide B - wood

Composition #10: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide B (RF-00011139-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide B - roots

Composition #11: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide B (RF-00011139-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide B - bark

Composition #12: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide A (RF-00011140-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide A - wood

Composition #13: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide C (RF-00011138-PAR)
Additional substance description:

5α, 17α-uzarigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide C - wood

Composition #14: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide C (RF-00011138-PAR)
Additional substance description:

5α, 17α-uzarigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide C - root

Composition #15: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide C (RF-00011138-PAR)
Additional substance description:

5α, 17α-uzarigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-sarmentopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide C - bark

Composition #16: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide E (RF-00011136-PAR)
Additional substance description:

5-epicannogeninic acid 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide E - wood

Composition #17: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide D (RF-00011137-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide D - wood

Composition #18: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide D (RF-00011137-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide D - bark

Composition #19: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide D (RF-00011137-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide D - root

Composition #20: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide E (RF-00011136-PAR)
Additional substance description:

5-epicannogeninic acid 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide E - root

Composition #21: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide E (RF-00011136-PAR)
Additional substance description:

5-epicannogeninic acid 3-O-[β-D-glucopyranosyl-(1→4)- β-D-boivinopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide E - bark

Composition #22: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide F (RF-00011135-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)-2-O-acetyl-β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide F - root

Composition #23: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide F (RF-00011135-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)-2-O-acetyl-β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide F - bark

Composition #24: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Boivinide F (RF-00011135-PAR)
Additional substance description:

corotoxigenin 3-O-[β-D-glucopyranosyl-(1→4)-2-O-acetyl-β-D-digitalopyranoside]
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

boivinide F - wood

Composition #25: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Stroboside (RF-00011272-PAR)
Additional substance description:

5a-corotoxigenin 3-O- β-D-boivinoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5a-corotoxigenin 3-O- β-D-boivinoside - wood

Composition #26: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Stroboside (RF-00011272-PAR)
Additional substance description:

5a-corotoxigenin 3-O- β-D-boivinoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5a-corotoxigenin 3-O- β-D-boivinoside - root

Composition #27: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Stroboside (RF-00011272-PAR)
Additional substance description:

5a-corotoxigenin 3-O- β-D-boivinoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5a-corotoxigenin 3-O- β-D-boivinoside - bark

Composition #28: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

Uzarigenin 3-O-α-L-rhamnoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

uzarigenin 3-O- α-L-rhamnoside - root

Composition #29: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

Uzarigenin 3-O-α-L-rhamnoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

uzarigenin 3-O- α-L-rhamnoside - wood

Composition #30: Karkare, Sampada., Adou, Eba., Cao, Shugeng., Brodie, Peggy., Miller, James S., Andrianjafy, N. M., Razafitsalama, J., Andriantsiferana, Rabodo., Rasamison, Vincent E., Kingston, David G. I. Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest. JOURNAL OF NATURAL PRODUCTS, 2007, vol. 70, no. 11, p. 1766–1770. DOI: 10.1021/np070336n. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

Uzarigenin 3-O-α-L-rhamnoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR and LC-HRESIMS analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

uzarigenin 3-O- α-L-rhamnoside - bark