EFSA Compendium of Botanicals

Draft - work in progress

Sphaerophysa salsula (Pall.) DC.

Family:: Fabaceae
Approval state:: Approved
Number of articles retrieved:: 78
Number of processed references:: 8

Compositions

#1: Guanidine derivative (spherophysine) #2: Isoflavones (stem) #3: Isoflavones (root) #4: Salicylic acid (root) #5: Salicylic acid (stem) #6: Isoflavones #7: Matrine #8: Alkaloids #9: stilbene #10: Guanidine derivatives (sphaerophysin A) #11: Saponins

Endpoint Studies

Genotoxicity

Composition #1: Krone, I., Reuter, Gerhard. Pharmacognostic studies of Sphaerophysa salsula with special consideration of the qualitative and quantitative determination of spherophysine. pharmazeutische zentralhalle fuer deutschland, 1967, p. 425–440. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

Guanidine derivatives (RF-00010830-PAR)
Additional substance description:

spherophysine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

ion exchange
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Guanidine derivative (spherophysine)

Composition #2: Li, Zhanlin., Lu, Xiaoyan., Meng, Dali., Li, Xi. Chemical constituents in roots and stems of Sphaerophysa salsula. zhongcaoyao, 2005, p. 25–26. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

isoflavones (RF-00004359-PAR)
Additional substance description:

4',7-dihydroxy-3'-methoxyisoflavone, formononetin, 4',7-dihydroxy-3'-methoxyisoflavone-7-O-β-D-glucopyranoside
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoflavones (stem)

Composition #3: Li, Zhanlin., Lu, Xiaoyan., Meng, Dali., Li, Xi. Chemical constituents in roots and stems of Sphaerophysa salsula. zhongcaoyao, 2005, p. 25–26. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

isoflavones (RF-00004359-PAR)
Additional substance description:

4',7-dihydroxy-3'-methoxyisoflavone, formononetin, 4',7-dihydroxy-3'-methoxyisoflavone-7-O-β-D-glucopyranoside
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoflavones (root)

Composition #4: Li, Zhanlin., Lu, Xiaoyan., Meng, Dali., Li, Xi. Chemical constituents in roots and stems of Sphaerophysa salsula. zhongcaoyao, 2005, p. 25–26. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Salicylic acid (RF-00000241-VET)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Salicylic acid (root)

Composition #5: Li, Zhanlin., Lu, Xiaoyan., Meng, Dali., Li, Xi. Chemical constituents in roots and stems of Sphaerophysa salsula. zhongcaoyao, 2005, p. 25–26. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Salicylic acid (RF-00000241-VET)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Salicylic acid (stem)

Composition #6: Li, Guoyu., Wang, Jinhui., Li, Xian., Li, Ning. Isolation and identification of pterocarpans and isoflavones from the pericarp of Sphaerophysa salsula DC.. zhongguo yaowu huaxue zazhi, 2003, p. 215–218. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

not specified
Substance:

isoflavones (RF-00004359-PAR)
Additional substance description:

4',7-dimethoxyisoflavone (daidzein di-Me ether; (-)-pterocarpin; (-)-10-methoxymedicarpin; and calycosin
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoflavones

Composition #7: Zhao, Qing-mei., Yu, Yong-tao., Ma, Yong-ping. Preliminary analysis on alkaloids of Swainsona salsula. zhongguo xumu shouyi, 2012, p. 135–139. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Matrine (RF-00003483-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC, phytochemical screening
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Matrine

Composition #8: Meng, Qing-yan., Chen, Yi-jun., Zhu, Xue-jiao. Acetylcholinesterase inhibitory activity of total alkaloids isolated from eight poisonous plants of Taim basin. guangpu shiyanshi, 2013, p. 2649–2651. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acid-base extraction followed by chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #9: Ma, ZJ., Li, X., Li, N., Wang, JH. Stilbenes from Sphaerophysa salsula. FITOTERAPIA, 2002, vol. 73, no. 4, p. 313–315. DOI: 10.1016/S0367-326X(02)00074-6. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Analytical method code:

Element spectroscopy (F051A)
Analytical method - additional description:

spectroscopic
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

stilbene

Composition #10: Ma, ZJ., Fujii, I., Ebizuka, Y., Li, X. A new lignan from the seeds of Sphaerophysa salsula. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2004, vol. 6, no. 4, p. 265–269. DOI: 10.1080/1028602031000147447. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Guanidine derivatives (RF-00010830-PAR)
Additional substance description:

Sphaerophysin A
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Guanidine derivatives (sphaerophysin A)

Composition #11: Ma, Z. -J., Wang, N., Fujii, I., Ebizuka, Y., Li, X. Two new 9,10-seco-cycloartanes from the seeds of Sphaerophysa salsula. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2006, vol. 8, no. 7, p. 657–661. DOI: 10.1080/10286020500246279. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Saponins (RF-00004333-PAR)
Additional substance description:

soyasaponin I and soyasaponin I 22-O-b-D-glucopyranoside
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins