EFSA Compendium of Botanicals

Draft - work in progress

Soymida febrifuga (Roxb.) A. Juss.

Family:: Meliaceae
Approval state:: Approved
Number of articles retrieved:: 80
Number of processed references:: 6

Compositions

#1: Catechol tannin #2: Calcium oxalate #3: tannins #4: Hydroxy-methoxy-3-(4′-hydroxybenzyl)coumarins #5: Homoisoflavanone derivatives #6: syomidin A and B #7: methyl angolensate #8: Limonoids

Endpoint Studies

Genotoxicity

Composition #1: Chowdary, P. S., Joseph, K. A., Padmanabhan, K. Soymida febrifuga bark as a suitable substitute for imported wattle bark. tanner, 1955, p. 15–21. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

Catechol tannin
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

15-20
Internal remarks:

Catechol tannin

Composition #2: Attarde, D. L., Chaudhari, B. J., Kale, S. S., Bhamber, R. S., Pal, S. C. Pharmacognostic studies on leaflets of Soymida febrifuga Adr. Juss. Family: Meliaceae. Journal of Pharmacy Research, 2010, p. 2435–2440. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Raw, no heat treatment (A07HS)
Substance:

Calcium oxalate (RF-00003960-PAR)
Analytical method code:

Microscopic detection (F536A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calcium oxalate

Composition #3: Attarde, D. L., Chaudhari, B. J., Kale, S. S., Bhamber, R. S., Pal, S. C. Pharmacognostic studies on leaflets of Soymida febrifuga Adr. Juss. Family: Meliaceae. Journal of Pharmacy Research, 2010, p. 2435–2440. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #4: Awale, Suresh., Miyamoto, Tatsuya., Linn, Thein Zaw., Li, Feng., Win, Nwet Nwet., Tezuka, Yasuhiro., Esumi, Hiroyasu., Kadota, Shigetoshi. Cytotoxic Constituents of Soymida febrifuga from Myanmar. journal of natural products, 2009, vol. 72, no. 9, p. 1631–1636. DOI: 10.1021/np9003323. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOH 70%; selective extraction; column chromatography
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

hydroxy-methoxy-3- (4′-hydroxybenzyl)coumarins
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, IR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Hydroxy-methoxy-3-(4′-hydroxybenzyl)coumarins

Composition #5: Awale, Suresh., Miyamoto, Tatsuya., Linn, Thein Zaw., Li, Feng., Win, Nwet Nwet., Tezuka, Yasuhiro., Esumi, Hiroyasu., Kadota, Shigetoshi. Cytotoxic Constituents of Soymida febrifuga from Myanmar. journal of natural products, 2009, vol. 72, no. 9, p. 1631–1636. DOI: 10.1021/np9003323. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOH 70%; selective extraction; column chromatography
Substance:

isoflavones (RF-00004359-PAR)
Additional substance description:

homoisoflavanone derivatives
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, IR, MS, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Homoisoflavanone derivatives

Composition #6: Yadav, P. Ashok., Suresh, G., Prasad, K. Rajendra., Rao, M. Suri Appa., Babu, K. Suresh. New phragmalin-type limonoids from Soymida febrifttga. TETRAHEDRON LETTERS, 2012, vol. 53, no. 7, p. 773–777. DOI: 10.1016/j.tetlet.2011.11.143. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

limonoids limonoids (RF-00004362-PAR)
Additional substance description:

syomidin A and B
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, HRESIMS, IR, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

syomidin A and B

Composition #7: ADESIDA, GA., TAYLOR, DAH. EXTRACTIVES FROM SOYMIDA-FEBRIFUGA. phytochemistry, 1972, vol. 11, no. 4, p. 1520–&. DOI: 10.1016/S0031-9422(00)90133-X. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

limonoids limonoids (RF-00004362-PAR)
Additional substance description:

methyl angolensate
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1
Internal remarks:

methyl angolensate

Composition #8: MALLAVARAPU, GR., MURALIKRISHNA, E., CONNOLLY, JD. 3 TETRANORTRITERPENOIDS FROM FRUITS OF SOYMIDA-FEBRIFUGA. PHYTOCHEMISTRY, 1985, vol. 24, no. 2, p. 305–307. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

limonoids limonoids (RF-00004362-PAR)
Additional substance description:

epoxyfebrinin B and derivatives, deoxyandirobin, febrinolide, methyl angolensate, 17-beta-hydroxy-6-alpha-acetoxyazadiradione
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

melting point, IR, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Limonoids