EFSA Compendium of Botanicals

Draft - work in progress

Sorbus aucuparia L.

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 1351
Number of processed references:: 2

Compositions

Endpoint Studies

#1: Proanthocyanidins - inhibition of amylase #2: Gastrointestinal disturbances (nausea and vomiting) linked to parasorbic acid

Genotoxicity

Endpoint study #1: Boath, Ashley S., Grussu, Dominic., Stewart, Derek., McDougall, Gordon J. Berry Polyphenols Inhibit Digestive Enzymes: a Source of Potential Health Benefits?. Food Digestion, 2012, p. 1–7. . [DOI link]

Study relevance:

Human health
Substance:

Proanthocyanidins (condensed tannins) Proanthocyanidins (condensed tannins) (RF-00004370-PAR)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

aqueous ethanol and acetone
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

inhibition of amylase
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

Proanthocyanidins - inhibition of amylase

Endpoint study #2: Veit, M., Martin, E. Major poisonous plants: Components and their pharmacology BEDEUTENDE GIFTPFLANZEN: INHALTSSTOFE UND IHRE PHARMAKOLOGIE . pharmazeutische zeitung, 1998, vol. 143, no. 26, p. 11–15. .

Study relevance:

Human health
Plant part:

Fruit unspecified (as part-nature) (A067D)
Preparation/Extraction method:

Raw, no heat treatment (A07HS)
Type of toxicological test:

case report (CHD060TT)
Tested organism:

Human (as organism) (A056J)
Sex:

No data
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

Digestive (TOX18A)
Target tissue:

digestive: Stomach (TT027A)
Effect description:

Gastrointestinal disturbances (nausea and vomiting) linked to parasorbic acid
Effect or parameter linked to the endpoint:

other (CHD003BE)
Internal remarks:

Gastrointestinal disturbances (nausea and vomiting) linked to parasorbic acid