EFSA Compendium of Botanicals

Draft - work in progress

Sophora denudata Bory

Family:: Fabaceae
Approval state:: Approved
Number of articles retrieved:: 9
Number of processed references:: 1

Compositions

#1: oxymatrine #2: cytisine #3: N-methylcytisine #4: baptifoline #5: anagyrine (quinolizidine alkaloids) #6: α-matrine

Endpoint Studies

Genotoxicity

Composition #1: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

Oxymatrine (RF-00010939-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

UV and IR spectroscopy
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

oxymatrine

Composition #2: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

Cytisine (RF-00003762-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cytisine

Composition #3: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

N-Methylcytisine (RF-00003492-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

UV and IR spectoscopy
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

N-methylcytisine

Composition #4: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

baptifoline (RF-00004172-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

UV and IR spectroscopy
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

baptifoline

Composition #5: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

Thermopsine (RF-00003604-PAR)
Additional substance description:

Anagyrine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anagyrine (quinolizidine alkaloids)

Composition #6: Faugeras, Guy., Paris, Rene., Peltier, Maurice. Alkaloids and polyphenols of leguminosae. XXVIII. Alkaloids of Sophora denudata endemic to Reunion Island. Annales Pharmaceutiques Francaises, 1973, p. 561568. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether (fat extraction)/methanol/methanol-tartaric acid
Substance:

Matrine (RF-00003483-PAR)
Additional substance description:

α-matrine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

UV and IR spectroscopy
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

α-matrine