EFSA Compendium of Botanicals

Draft - work in progress

Solidago gigantea Aiton

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 325
Number of processed references:: 6

Compositions

#1: Giganteasaponin #2: giganteasaponins 1-4 #3: Myrcene #4: Myrcene #5: cis-Clerodane derivatives #6: Solidagoic acid A #7: giganteasaponins 1 — 4 #8: saponins

Endpoint Studies

Genotoxicity

Composition #1: Reznicek, G., Jurenitsch, J., Michl, G., Haslinger, E. The first structurally confirmed saponin from Solidago gigantea: structure elucidation by modern NMR techniques. Tetrahedron Letters, 1989, p. 4097–4100. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (80%)
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

Giganteasaponin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Giganteasaponin

Composition #2: Hiller, K., Bader, G., Reznicek, G., Jurenitsch, J., Kubelka, W. The main saponins of medicinally used species of the genus Solidago. pharmazie, 1991, p. 405–408. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

giganteasaponins 1-4
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

giganteasaponins 1-4

Composition #3: Kalemba, D., Marschall, H., Bradesi, P. Constituents of the essential oil of Solidago gigantea Ait. (giant goldenrod). FLAVOUR AND FRAGRANCE JOURNAL, 2001, vol. 16, no. 1, p. 19–26. DOI: 10.1002/1099-1026(200101/02)16:1<19::AID-FFJ940>3.0.CO;2-U. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.6
Internal remarks:

Myrcene

Composition #4: Johnson, Robert H., Hull-Sanders, Helen M., Meyer, Gretchen A. Comparison of foliar terpenes between native and invasive Solidago gigantea. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2007, vol. 35, no. 12, p. 821–830. DOI: 10.1016/j.bse.2007.06.005. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

30% EtOAc in hexane
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Myrcene

Composition #5: Johnson, Robert H., Hull-Sanders, Helen M., Meyer, Gretchen A. Comparison of foliar terpenes between native and invasive Solidago gigantea. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2007, vol. 35, no. 12, p. 821–830. DOI: 10.1016/j.bse.2007.06.005. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

30% EtOAc in hexane
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

cis-Clerodane derivatives
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cis-Clerodane derivatives

Composition #6: Johnson, Robert H., Hull-Sanders, Helen M., Meyer, Gretchen A. Comparison of foliar terpenes between native and invasive Solidago gigantea. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2007, vol. 35, no. 12, p. 821–830. DOI: 10.1016/j.bse.2007.06.005. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

30% EtOAc in hexane
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

Solidagoic acid A
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Solidagoic acid A

Composition #7: REZNICEK, G., JURENITSCH, J., KUBELKA, W., MICHL, G., KORHAMMER, S., HASLINGER, E. ISOLATION AND STRUCTURE OF THE 4 MAIN SAPONINS FROM SOLIDAGO-GIGANTEA VAR SEROTINA . liebigs annalen der chemie, 1990, no. 10, p. 989–994. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

giganteasaponins 1 — 4
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

giganteasaponins 1 — 4

Composition #8: Reznicek, G., Freiler, M., Schader, M., Schmidt, U. Determination of the content and the composition of the main saponins from Solidago gigantea AIT. Using high-performance liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1996, vol. 755, no. 1, p. 133–137. DOI: 10.1016/S0021-9673(96)00571-7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (80%)
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.8 -1.9
Internal remarks:

saponins