EFSA Compendium of Botanicals
Draft
- work in progress
Solanum robustum H.L. Wendl.
Solanum robustum H.L. Wendl.
Family:
Solanaceae
Approval state:
Approved
Number of articles retrieved:
12
Number of processed references:
3
Compositions
#1: beta-solamargine
#2: N-hydroxysolasodine
#3: solasodine
#4: robustine
#5: N-hydroxyrobustine
#6: 25-acetoxyrobustine
#7: solasodine
#8: N-hydroxysolasodine
#9: steroidal alkaloids
#10: solamargine
#11: solasonine
#12: N-hydroxyrobustine
#13: N-hydroxysolamargine
Endpoint Studies
Genotoxicity
Composition #1
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
solamargine (RF-00003581-PAR)
Additional substance description:
Solasodine glycosides
Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:
melting point, optical rotations, NMR, liquid secondary ion and electron impact MS, column chromatography, TLC
Result unit:
Percent (G138A)
Result type:
Numerical Value (VAL)
Value (concentration, content):
0.12
Internal remarks:
beta-solamargine
Composition #2
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
N-hydroxysolasodine (RF-00011363-PAR)
Additional substance description:
Steroidal alkaloids
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
N-hydroxysolasodine
Composition #3
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
solasodine (RF-00003583-PAR)
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
solasodine
Composition #4
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
robustine (RF-00011357-PAR)
Additional substance description:
Solasodine glycosides
Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:
melting point, optical rotations, NMR, liquid secondary ion and electron impact MS, column chromatography, TLC
Result unit:
Percent (G138A)
Result type:
Numerical Value (VAL)
Value (concentration, content):
0.37
Internal remarks:
robustine
Composition #5
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
N-hydroxyrobustine (RF-00010969-PAR)
Additional substance description:
Solasodine glycosides
Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:
melting point, optical rotations, NMR, liquid secondary ion and electron impact MS, column chromatography, TLC
Result unit:
Percent (G138A)
Result type:
Numerical Value (VAL)
Value (concentration, content):
0.20
Internal remarks:
N-hydroxyrobustine
Composition #6
: Ripperger, Helmut., Porzel, Andrea. Solanum alkaloids, 128. Steroid alkaloid glycosides from Solanum robustum. Liebigs Annalen der Chemie, 1994, vol. 0, no. 5, p. 517–520. . [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
Quinoline alkaloids (RF-00004326-PAR)
Additional substance description:
25-acetoxyrobustine
Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:
melting point, optical rotations, NMR, liquid secondary ion and electron impact MS, column chromatography, TLC
Result unit:
Percent (G138A)
Result type:
Numerical Value (VAL)
Value (concentration, content):
0.16
Internal remarks:
25-acetoxyrobustine
Composition #7
: RIPPERGER, H., PORZEL, A. SOLANUM ALKALOIDS .123. N-HYDROXYSOLASODINE FROM SOLANUM-ROBUSTUM. PHYTOCHEMISTRY, 1992, vol. 31, no. 5, p. 1837–1839. DOI: 10.1016/0031-9422(92)83164-T. [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
solasodine (RF-00003583-PAR)
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
1H and 13C NMR, 1H-1H COSY 2D NMR, HR-MS, TLC
Result unit:
Percent (G138A)
Result type:
Numerical Value (VAL)
Value (concentration, content):
0.36
Internal remarks:
solasodine
Composition #8
: RIPPERGER, H., PORZEL, A. SOLANUM ALKALOIDS .123. N-HYDROXYSOLASODINE FROM SOLANUM-ROBUSTUM. PHYTOCHEMISTRY, 1992, vol. 31, no. 5, p. 1837–1839. DOI: 10.1016/0031-9422(92)83164-T. [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
N-hydroxysolasodine (RF-00011363-PAR)
Additional substance description:
Steroidal alkaloid
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
1H and 13C NMR, 1H-1H COSY 2D NMR, HR-MS, TLC
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
N-hydroxysolasodine
Composition #9
: RIPPERGER, H., PORZEL, A. SOLANUM ALKALOIDS .123. N-HYDROXYSOLASODINE FROM SOLANUM-ROBUSTUM. PHYTOCHEMISTRY, 1992, vol. 31, no. 5, p. 1837–1839. DOI: 10.1016/0031-9422(92)83164-T. [
DOI link
]
Language:
English (en)
Plant part:
Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
Steroidal alkaloids (RF-00004336-PAR)
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
1H and 13C NMR, 1H-1H COSY 2D NMR, HR-MS, TLC
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
steroidal alkaloids
Composition #10
: RIPPERGER, H. STEROID ALKALOID GLYCOSIDES FROM SOLANUM-ROBUSTUM .134. SOLANUM ALKALOIDS. PHYTOCHEMISTRY, 1995, vol. 39, no. 6, p. 1475–1477. DOI: 10.1016/0031-9422(95)00150-6. [
DOI link
]
Language:
English (en)
Plant part:
Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
solamargine (RF-00003581-PAR)
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
LSI-MS, 1H-NMR, 13C NMR, TLC, column chromatography
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
solamargine
Composition #11
: RIPPERGER, H. STEROID ALKALOID GLYCOSIDES FROM SOLANUM-ROBUSTUM .134. SOLANUM ALKALOIDS. PHYTOCHEMISTRY, 1995, vol. 39, no. 6, p. 1475–1477. DOI: 10.1016/0031-9422(95)00150-6. [
DOI link
]
Language:
English (en)
Plant part:
Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
solasonine (RF-00003584-PAR)
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
LSI-MS, 1H-NMR, 13C NMR, TLC, column chromatography
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
solasonine
Composition #12
: RIPPERGER, H. STEROID ALKALOID GLYCOSIDES FROM SOLANUM-ROBUSTUM .134. SOLANUM ALKALOIDS. PHYTOCHEMISTRY, 1995, vol. 39, no. 6, p. 1475–1477. DOI: 10.1016/0031-9422(95)00150-6. [
DOI link
]
Language:
English (en)
Plant part:
Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
N-hydroxyrobustine (RF-00010969-PAR)
Additional substance description:
Solasodine glycosides
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
LSI-MS, 1H-NMR, 13C NMR, TLC, column chromatography
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
N-hydroxyrobustine
Composition #13
: RIPPERGER, H. STEROID ALKALOID GLYCOSIDES FROM SOLANUM-ROBUSTUM .134. SOLANUM ALKALOIDS. PHYTOCHEMISTRY, 1995, vol. 39, no. 6, p. 1475–1477. DOI: 10.1016/0031-9422(95)00150-6. [
DOI link
]
Language:
English (en)
Plant part:
Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:
Solvent extraction (A0BZR)
Additional extraction description:
methanol
Substance:
N-Hydroxysolamargine (RF-00011362-PAR)
Additional substance description:
Solasodine glycosides
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:
LSI-MS, 1H-NMR, 13C NMR, TLC, column chromatography
Yes/No Qualitative:
Positive/Present (POS)
Result type:
Qualitative Value (Binary) (BIN)
Internal remarks:
N-hydroxysolamargine
