Draft - work in progress
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- Jurubeba (as plant) // Solanum paniculatum L.
Jurubeba (as plant) // Solanum paniculatum L.
- Family:
- Solanaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 112
- Number of processed references:
- 5
Composition #1: Cambiaghi, Stefano., Dradi, Emanuele., Longo, Rocco. Structure and absolute configuration of new alkaloids from Solanum paniculatum. annali di chimica (rome, italy), 1971, p. 99–111. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
EtOH
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Substance:
Steroidal spirostane saponins Steroidal spirostane saponins (RF-00004321-PAR)
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Steroidal spirostane saponins
Composition #2: Vieira, Pabline M., Marinho, Lorena P. M., Ferri, Suzana C. S., Chen-Chen, Lee. Protective effects of steroidal alkaloids isolated from Solanum paniculatum L. against mitomycin cytotoxic and genotoxic actions. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2013, vol. 85, no. 2, p. 553–560. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol
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Substance:
steroidal saponins (RF-00010818-PAR)
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Additional substance description:
jurubine
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
jurubine
Composition #3: Soares, V., de Souza, G. R., Menezes, C. P., da Silva, A. J. R. Alkaloids from Solanum paniculatum L. leaves. planta medica, 2014, vol. 80, no. 16, p. 1503–1503. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Unspecified
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Substance:
steroidal furostan saponins steroidal furostan saponins (RF-00004397-PAR)
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Analytical method code:
HPLC with standard detection methods (F019A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Steroidal furostan saponins
Composition #4: Vieira Junior, Gerardo Magela., da Rocha, Claudia Quintino., Rodrigues, Tamires de Souza., Hiruma-Lima, Clelia Akiko., Vilegas, Wagner. New steroidal saponins and antiulcer activity from Solanum paniculatum L.. FOOD CHEMISTRY, 2015, vol. 186, p. 160–167. DOI: 10.1016/j.foodchem.2014.08.005.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol
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Substance:
steroidal saponins (RF-00010818-PAR)
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Additional substance description:
Diosgenin b-D-glucopiranoside
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Diosgenin b-D-glucopiranoside
Endpoint study
#1: de Sousa Guarana, Eduardo Levi., Riet-Correa, Franklin., de Mendonca, Carla Lopes., Medeiros, Rosane M. T., Costa, Nivaldo de Azevedo., Bastos Afonso, Jose Augusto. Poisoning by Solanum paniculatum (Solanaceae) in cattle. pesquisa veterinaria brasileira, 2011, vol. 31, no. 1, p. 59–64. .
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Study relevance:
Animal (target species) health
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Plant part:
Live plants (as part-nature) (A0BA0)
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Type of toxicological test:
case report (CHD060TT)
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Tested organism:
Cattle (as animal) (A057E)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
NEUROTOXICITY (TOX04A)
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Target tissue:
neurologic: Central Nervous System (TT035A)
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Effect description:
transitory, periodic attacks with loss of balance, incoordinated gait, neck and head extension, hypermetria, intention tremors, nystagmus, and falls
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Effect or parameter linked to the endpoint:
neurology (CHD027BE)
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Internal remarks:
CNS neurotoxicity
