Composition #1: Ferreira, ICFD., Vargas, VMF. Mutagenicity of medicinal plant extracts in Salmonella/microsome assay. phytotherapy research, 1999, vol. 13, no. 5, p. 397–400. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins
Genotox #1: Ferreira, ICFD., Vargas, VMF. Mutagenicity of medicinal plant extracts in Salmonella/microsome assay. phytotherapy research, 1999, vol. 13, no. 5, p. 397–400. .
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Study category:
Mutagenicity
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Type of toxicological test:
bacterial gene mutation assay (CHD027TT)
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Tested organism:
Salmonella typhimurium (as organism) (A0CPZ)
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Strain of test organism:
TA 98 (CHD029ST)
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Exogenous metabolic activation applied:
with and without
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Endpoint measured:
gene mutation
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Remarks on genotox study:
signs of increased mutagenic induction
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Internal remarks:
mutagenic in Salmonella typhimurium (TA98)
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Internal ID:
WOS:000082182900007
