EFSA
ecomole
vscht
  2. Senecio vulgaris L.

Senecio vulgaris L.

Family:
Asteraceae
Approval state:
Approved
Number of articles retrieved:
1007
Number of processed references:
5
Compositions
#1: Free pyrrolizidine alkaloids #2: Total pyrrolizidine alkaloids #3: Retrorsine #4: Seneciphylline #5: Senecionine #6: Senkirkine #7: Pyrrolizidine alkaloids
Endpoint Studies
#1: hepatotoxicity in horses #2: hepatotoxicity
Genotoxicity
Composition #1: Molyneux, Russell J., Johnson, A. Earl., Roitman, James N., Benson, Mabry E. Chemistry of toxic range plants. Determination of pyrrolizidine alkaloid content and composition in Senecio species by nuclear magnetic resonance spectroscopy. Journal of Agricultural and Food Chemistry, 1979, p. 494–499. .
Composition #2: Molyneux, Russell J., Johnson, A. Earl., Roitman, James N., Benson, Mabry E. Chemistry of toxic range plants. Determination of pyrrolizidine alkaloid content and composition in Senecio species by nuclear magnetic resonance spectroscopy. Journal of Agricultural and Food Chemistry, 1979, p. 494–499. .
Composition #3: Zhou, Yan., Li, Na., Choi, Franky Fung-Kei., Qiao, Chun-Feng., Song, Jing-Zheng., Li, Song-Lin., Liu, Xin., Cai, Zong-Wei., Fu, Peter P., Lin, Ge., et al. A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-​containing plants by using ultra performance liquid chromatography-​tandem quadrupole mass spectrometry. Analytica Chimica Acta, 2010, p. 33–40. .
Composition #4: Zhou, Yan., Li, Na., Choi, Franky Fung-Kei., Qiao, Chun-Feng., Song, Jing-Zheng., Li, Song-Lin., Liu, Xin., Cai, Zong-Wei., Fu, Peter P., Lin, Ge., et al. A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-​containing plants by using ultra performance liquid chromatography-​tandem quadrupole mass spectrometry. Analytica Chimica Acta, 2010, p. 33–40. .
Composition #5: Zhou, Yan., Li, Na., Choi, Franky Fung-Kei., Qiao, Chun-Feng., Song, Jing-Zheng., Li, Song-Lin., Liu, Xin., Cai, Zong-Wei., Fu, Peter P., Lin, Ge., et al. A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-​containing plants by using ultra performance liquid chromatography-​tandem quadrupole mass spectrometry. Analytica Chimica Acta, 2010, p. 33–40. .
Composition #6: Zhou, Yan., Li, Na., Choi, Franky Fung-Kei., Qiao, Chun-Feng., Song, Jing-Zheng., Li, Song-Lin., Liu, Xin., Cai, Zong-Wei., Fu, Peter P., Lin, Ge., et al. A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-​containing plants by using ultra performance liquid chromatography-​tandem quadrupole mass spectrometry. Analytica Chimica Acta, 2010, p. 33–40. .
Composition #7: Roeder, E., Wiedenfeld, H. Plants containing pyrrolizidine alkaloids used in the Traditional Indian Medicine - including Ayurveda. PHARMAZIE, 2013, vol. 68, no. 2, p. 83–92. DOI: 10.1691/ph.2013.2706. [DOI link]
Endpoint study #1: Lessard P., Wilson W D., Olander H J., Rogers Q R., Mendel V E. Clinicopathologic study of horses surviving pyrrolizidine alkaloid (Senecio vulgaris) toxicosis. american journal of veterinary research, 1986, p. 1776–1780. .
Endpoint study #2: Xiong, Aizhen., Fang, Lianxiang., Yang, Xiao., Yang, Fan., Qi, Meng., Kang, Hong., Yang, Li., Tsim, Karl Wah-Keung., Wang, Zhengtao. An application of target profiling analyses in the hepatotoxicity assessment of herbal medicines: comparative characteristic fingerprint and bile acid profiling of Senecio vulgaris L. and Senecio scandens Buch.-Ham. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2014, vol. 406, no. 29, p. 7715–7727. DOI: 10.1007/s00216-014-8175-z. [DOI link]