EFSA Compendium of Botanicals

Draft - work in progress

Rosa laevigata Michx.

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 438
Number of processed references:: 6

Compositions

#1: Tannins in seeds (pericarp) #2: Scopoletin (coumarin) in leaves #3: Saponins in roots #4: Tannins in fruits #5: Condensed tannins in roots #6: p-coumaric acid in the aerial part #7: 5,6-dimethoxy coumarin in the aerial part

Endpoint Studies

Genotoxicity

Composition #1: Yoshida, Takashi., Tanaka, Katsumi., Chen, Xin-Min., Okuda, Takuo. Tannins of rosaceous medicinal plants. Part 7. Dimeric ellagitannins, laevigatins E, F and G, from Rosa laevigata. phytochemistry, 1989, p. 2451–2454. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

laevigatins B, D,E, F and G, agrimonic acid B, sanguiin H-4, pedunculagin and agrimoniin in pericarp
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in seeds (pericarp)

Composition #2: Wu, Jian-lin., Wang, Ping., Gao, Peng., Zeng, Na., Liu, Xiang-fang., Wang, Shu-yi., Shen, Yang., Xu, Chao-dou. Studies on the chemical constituents in leaves of Rosa Laevigata michx. yaoxue shijian zazhi, 2012, p. 275–278. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scopoletin (coumarin) in leaves

Composition #3: Chen, Yuyan., Li, Bin., Li, Shunxiang., Zou, Qian. Extraction and purification technologies of total saponins from RADIX ROSAE LAEVIGATAE. medicinal plant, 2013, p. 17–21. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% EtOH
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in roots

Composition #4: Yan, Jianxin., Wang, Xiaoli. Analysis of influence factors on extraction rate of tannin from Rosa Laevigatae Fructus and optimization of extraction condition. zhongguo yiyao daobao, 2015, p. 99–102. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

75% EtOH
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in fruits

Composition #5: Yan, Guoqing., Li, Shiping., Hu, Jun., Zhai, Xiangyu., Ma, Wei., Li, Ning., Wang, Kaijin. Phenolic constituents from the roots of Rosa laevigata (Rosaceae). BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2014, vol. 52, p. 23–26. DOI: 10.1016/j.bse.2013.09.006. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 80%
Substance:

Proanthocyanidins (condensed tannins) Proanthocyanidins (condensed tannins) (RF-00004370-PAR)
Additional substance description:

procyanidin B3, fisetinidol-(4a, 8)-catechin, guibourtinidol- (4a, 8)-catechin, ent- isetinidol -(4a, 6)-catechin, fisetinidol-(4b, 8)-catechin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR + MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Condensed tannins in roots

Composition #6: FANG, JM., WANG, KC., CHENG, YS. THE CHEMICAL-CONSTITUENTS FROM THE AERIAL PART OF ROSA-LAEVIGATA. journal of the chinese chemical society, 1991, vol. 38, no. 3, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethyl acetate
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

p-coumaric acid in the aerial part

Composition #7: FANG, JM., WANG, KC., CHENG, YS. THE CHEMICAL-CONSTITUENTS FROM THE AERIAL PART OF ROSA-LAEVIGATA. journal of the chinese chemical society, 1991, vol. 38, no. 3, p. 297–299. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethyl acetate
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

5,6-dimethoxy-coumarin
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5,6-dimethoxy coumarin in the aerial part