Draft - work in progress
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- Rhamnus alpina L.
Rhamnus alpina L.
- Family:
- Rhamnaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 21
- Number of processed references:
- 2
Composition #1: Marangoni, P. Italian Rhamnus. III. Rhamnus alaternus L., Rhamnus oleoides L., and Rhamnus alpina L. Bollettino - Societa Italiana di Biologia Sperimentale, 1946, p. 264–266. .
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Plant part:
Bark (as part-nature) (A066X)
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Substance:
anthracene derivatives (RF-00004342-PAR)
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Analytical method - additional description:
Maurin method
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.9-5.4
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Internal remarks:
Anthraglycosides
Composition #2: Corona, G. L., Arbasino, M. Chemical and pharmacological research on Rhamnus alpina. Fitoteropia, 1963, p. 73–8; 83. .
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Plant part:
Bark (as part-nature) (A066X)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
anthracene derivatives (RF-00004342-PAR)
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Additional substance description:
Anthraglycosides
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Analytical method - additional description:
method of Fairbairn (F. and Mahran, CA 48, 1627i)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Dry matter (B002A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
4.89
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Internal remarks:
Anthraglycosides
Composition #3: Corona, G. L., Arbasino, M. Chemical and pharmacological research on Rhamnus alpina. Fitoteropia, 1963, p. 73–8; 83. .
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Plant part:
Bark (as part-nature) (A066X)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Water
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Substance:
anthraquinones (RF-00004343-PAR)
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Analytical method - additional description:
method of Fairbairn (F. and Mahran, CA 48, 1627i)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Dry matter (B002A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
8.19
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Internal remarks:
Anthraquinones
Endpoint study
#1: Corona, G. L., Arbasino, M. Chemical and pharmacological research on Rhamnus alpina. Fitoteropia, 1963, p. 73–8; 83. .
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Study relevance:
Human health
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Substance:
anthracene derivatives (RF-00004342-PAR)
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Plant part:
Stem / stalk (as part-nature) (A067S)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
water extract of stem bark - anthraglycosides
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Type of toxicological test:
acute toxicity (CHD016TT)
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Tested organism:
House mouse (as animal) (A0CNT)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Number of organisms dosed:
10
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
Liquid faeces
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Effect or parameter linked to the endpoint:
food efficiency (CHD021BE)
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Internal remarks:
purgative
