EFSA Compendium of Botanicals

Draft - work in progress

Ptychopetalum olacoides Benth.

Family:: Olacaceae
Approval state:: Approved
Number of articles retrieved:: 104
Number of processed references:: 4

Compositions

#1: Camphor #2: Eugenol #3: Protocatechuic acid #4: Theobromine #5: neoclerodane diterpenes

Endpoint Studies

Genotoxicity

Composition #1: Bucek, E. Uber., Fournier, G., Dadoun, H. Volatile constituents of Ptychopetalum olacoides root oil. Planta Medica, 1987 . .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.2
Internal remarks:

Camphor

Composition #2: Ito, Yuji., Hirayama, Fusayoshi., Aikawa, Yoko., Kondo, Hideaki., Sagara, Kazuhiko., Shoji, Junzo. Constituents from Muira-puama (the roots of Ptychopetalum olacoides).. Natural Medicines, 1995 . .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH, Hexane
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (Q) (F344A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Eugenol

Composition #3: Colombo, Renata., Batista, Andrea N. de L., Bomfim, Giovani C. C., Burgos, Rosilene C. R., Cavalheiro, Alberto J., Bolzani, Vanderlan da Silva., Silva, Dulce Helena S., Reimberg, Maria Celia H. Validated high-performance liquid chromatographic method for the standardisation of Ptychopetalum olacoides Benth., Olacaceae, commercial extracts. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2010, vol. 20, no. 5, p. 781–788. DOI: 10.1590/S0102-695X2010005000027. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (40%)
Substance:

3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
Additional substance description:

Protocatechuic acid
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Protocatechuic acid

Composition #4: Colombo, Renata., Batista, Andrea N. de L., Bomfim, Giovani C. C., Burgos, Rosilene C. R., Cavalheiro, Alberto J., Bolzani, Vanderlan da Silva., Silva, Dulce Helena S., Reimberg, Maria Celia H. Validated high-performance liquid chromatographic method for the standardisation of Ptychopetalum olacoides Benth., Olacaceae, commercial extracts. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2010, vol. 20, no. 5, p. 781–788. DOI: 10.1590/S0102-695X2010005000027. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (40%)
Substance:

Theobromine (RF-00000334-TOX)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Theobromine

Composition #5: Tang, Wanxia., Harada, Kenichi., Kubo, Miwa., Hioki, Hideaki., Fukuyama, Yoshiyasu. Eight New Clerodane Diterpenoids from the Bark of Ptychopetalum olacoides . natural product communications, 2011, vol. 6, no. 3, p. 327–332. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

clerodane-type diterpenes (RF-00004350-PAR)
Additional substance description:

kolavelool and derivatives, kolavenol, hardwickiic acid and derivatives ptychonolide, ptycholides I to IV
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

neoclerodane diterpenes