EFSA Compendium of Botanicals

Draft - work in progress

Pteris vittata L.

Family:: Pteridaceae
Approval state:: Approved
Number of articles retrieved:: 1134
Number of processed references:: 3

Compositions

#1: Isoflavones #2: saponins #3: Alkaloids

Endpoint Studies

Genotoxicity

#1: Fern spore extracts can cause DNA damage in human cells in vitro.

Composition #1: Xiong, Junjuan., Ding, Lijun. Qualitative analysis on effective constituents of Pteris vittata and its ultraviolet spectrophotometry. shizhen guoyi guoyao, 2011, p. 2623–2625. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water, ethanol and acid ethanol
Substance:

isoflavones (RF-00004359-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoflavones

Composition #2: Herin Sheeba Gracelin, D., John de Britto, A., Benjamin Jeya Rathna Kumar, P. Qualitative and quantitative analysis of phytochemicals in five Pteris species. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL.1, p. 105–107. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.40
Internal remarks:

saponins

Composition #3: Herin Sheeba Gracelin, D., John de Britto, A., Benjamin Jeya Rathna Kumar, P. Qualitative and quantitative analysis of phytochemicals in five Pteris species. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL.1, p. 105–107. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.10
Internal remarks:

Alkaloids

Genotox #1: Siman, SE., Povey, AC., Ward, TH., Margison, GP., Sheffield, E. Fern spore extracts can damage DNA. BRITISH JOURNAL OF CANCER, 2000, vol. 83, no. 1, p. 69–73. .

Study category:

Genotoxicity
Type of toxicological test:

single cell gel/comet assay in mammalian cells for detection of DNA damage (CHD040TT)
Method type:

in vitro
Tested organism:

Human (as organism) (A056J)
Strain of test organism:

leukemia cells (HL-60) (CHD052ST)
Sex:

No data
Exogenous metabolic activation applied:

no data
Control groups used:

yes
Is genotoxic:

Positive
Remarks on genotox study:

Fern spore extracts can cause DNA damage in human cells in vitro.
Internal remarks:

Fern spore extracts can cause DNA damage in human cells in vitro.
Internal ID:

WOS:000087632000012