EFSA Compendium of Botanicals

Draft - work in progress

Pseudelephantopus spicatus (B.Juss. ex Aubl.) Rohr ex C.F.Baker

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 9
Number of processed references:: 2

Compositions

#1: Alkaloids #2: Tannins #3: (+)-8,13-Diacetyl-piptocarphol

Endpoint Studies

Genotoxicity

Composition #1: Khatun, A., Rahman, M., Haque, T., Rahman, M.M., Akter, M., Akter, S., Jhumur, A. Cytotoxicity potentials of eleven Bangladeshi medicinal plants. Scientific World Journal, 2014, vol. 2014 . DOI: 10.1155/2014/913127. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol extract
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method - additional description:

preliminary screening
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #2: Khatun, A., Rahman, M., Haque, T., Rahman, M.M., Akter, M., Akter, S., Jhumur, A. Cytotoxicity potentials of eleven Bangladeshi medicinal plants. Scientific World Journal, 2014, vol. 2014 . DOI: 10.1155/2014/913127. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol extract
Substance:

Tannins (RF-00004337-PAR)
Analytical method - additional description:

preliminary screening
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #3: Odonne, G., Herbette, G., Eparvier, V., Bourdy, G., Rojas, R., Sauvain, M., Stien, D. Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru). Part III. JOURNAL OF ETHNOPHARMACOLOGY, 2011, vol. 137, no. 1, p. 875879. DOI: 10.1016/j.jep.2011.07.008. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Diacetylpiptocarphol (RF-00010918-PAR)
Additional substance description:

sesquiterpene lactone (hirsutinolide)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

HPLC-photodiode array absorbance detector, 1H and 13C NMR/2D NMR (COSY, NOESY, HSQC, HMBC), HREI-MS (orthogonal acceleraion time-of-flight mass analyser)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

(+)-8,13-Diacetyl-piptocarphol