Composition #1: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. Genistin (HMDB33988).. human metabolome database, 2012, vol. 3.0 . .
-
-
Plant part:
Unspecified (A07XD)
-
Additional extraction description:
unspecified
-
Substance:
genistin (RF-00003829-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
genistin
Composition #2: Repasi, J., Frank, L. Analytic and biological standardization of Prunus avium extracts .. acta pharmaceutica hungarica, 1992, vol. 62, no. 4, p. 172–81. .
-
-
Plant part:
Stem / stalk (as part-nature) (A067S)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
acetone
-
Substance:
isoflavones (RF-00004359-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Isoflavones in peduncles
Endpoint study
#1: Sisodia, R., Sharma, K.V., Singh, S. Acute toxicity effects of prunus avium fruit extract and selection of optimum dose against radiation exposure. journal of environmental pathology, toxicology and oncology, 2009, vol. 28, no. 4, p. 303–309. .
-
Study relevance:
Human health
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Additional plant/substance description:
methanol
-
Type of toxicological test:
short-term toxicity (CHD017TT)
-
Tested organism:
House mouse (as animal) (A0CNT)
-
Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
-
-
Unit of exposure duration:
Day (G134A)
-
Endpoint measured:
Dose producing lethality in 50% of experimental organisms (CHD024EP)
-
Concentration unit:
Grams per kilogram body weight (G226A)
-
Effect concentration:
4.947
-
Critical effect:
SYSTEMIC (TOX01A)
-
Effect description:
LD50 of the methanolic extract was calculated to be 4.947 gm/kg body weight
-
Effect or parameter linked to the endpoint:
mortality (CHD010BE)
-
Internal remarks:
LD50 of the methanolic extract was calculated to be 4.947 gm/kg body weight
