EFSA Compendium of Botanicals

Draft - work in progress

Pinus cembra L.

Family:: Pinaceae
Approval state:: Approved
Number of articles retrieved:: 842
Number of processed references:: 2

Compositions

#1: Lignans #2: Lariciresinol (knots, i.e. trunk)

Endpoint Studies

Genotoxicity

Composition #1: Smeds, AI., Hakala, K., Hurmerinta, TT., Kortela, L., Saarinen, NM., Makela, SI. Determination of plant and enterolignans in human serum by high-performance liquid chromatography with tandem mass spectrometric detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2006, vol. 41, no. 3, p. 898–905. DOI: 10.1016/j.jpba.2005.12.036. [DOI link]

Language:

English (en)
Plant part:

Trunk (as part-nature) (A166N)
Substance:

lignans (RF-00004361-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS/MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans

Composition #2: Saarinen, Niina M., Warri, Anni., Dings, Ruud P. M., Airio, Maarit., Smeds, Annika I., Makela, Sari. Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats. INTERNATIONAL JOURNAL OF CANCER, 2008, vol. 123, no. 5, p. 1196–1204. DOI: 10.1002/ijc.23614. [DOI link]

Language:

English (en)
Plant part:

Trunk (as part-nature) (A166N)
Additional extraction description:

unspecified
Substance:

lariciresinol (RF-00011086-PAR)
Additional substance description:

knots, i.e. trunk
Analytical method code:

Gaschromatography (GC) (F037A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lariciresinol (knots, i.e. trunk)