EFSA
ecomole
vscht
  2. Petiveria alliacea L.

Petiveria alliacea L.

Family:
Phytolaccaceae
Approval state:
Approved
Number of articles retrieved:
261
Number of processed references:
7
Compositions
#1: Coumarins #2: Tannins #3: Asarone #4: trans-Z-alpha- Bisabolene epoxide #5: Alkaloids
Endpoint Studies
#1: mice treated with a dose of 8000 mg/kg ptosis and ataxia, although none of the animals died, thereby demonstrating the low toxicity of this extract #2: the oral administration of 100–400 mg/kg of the P. alliacea root extract showed low acute toxicity #3: anxiogenic-like effect #4: retard in the implantation process
Genotoxicity
#1: significant dose dependent increase of sister chromatid exchange
Composition #1: Fontoura, M. C. P., Silva, S. do N., Abreu, I. C., Goncalves, J. R. dos S., Borges, M. O. da R., Borges, A. C. R. Effect of Petiveria alliacea L. in the intestinal secretion and motility of rodents. . revista brasileira de plantas medicinais, 2005, vol. 7, no. 2, p. 37–43. .
Composition #2: Fontoura, M. C. P., Silva, S. do N., Abreu, I. C., Goncalves, J. R. dos S., Borges, M. O. da R., Borges, A. C. R. Effect of Petiveria alliacea L. in the intestinal secretion and motility of rodents. . revista brasileira de plantas medicinais, 2005, vol. 7, no. 2, p. 37–43. .
Composition #3: Sathiyabalan, G., Packia, Lincy M., Muthukumarasamy, S., Mohan, V. R. GC-​MS analysis of bioactive components of Petiveria alliacea L. whole plant (phytolaccaceae). International Journal of Pharma Research and Health Sciences, 2014, p. 387–392. .
Composition #4: Sathiyabalan, G., Packia, Lincy M., Muthukumarasamy, S., Mohan, V. R. GC-​MS analysis of bioactive components of Petiveria alliacea L. whole plant (phytolaccaceae). International Journal of Pharma Research and Health Sciences, 2014, p. 387–392. .
Composition #5: Coe, F.G., Parikh, D.M., Johnson, C.A., Anderson, G.J. The good and the bad: Alkaloid screening and brineshrimp bioassays of aqueous extracts of 31 medicinal plants of eastern Nicaragua. Pharmaceutical Biology, 2012, vol. 50, no. 3, p. 384–392. DOI: 10.3109/13880209.2011.608077. [DOI link]
Endpoint study #1: Luz DA., Pinheiro AM., da Silva ML., Monteiro MC., Prediger RD., Ferraz Maia CS., Fontes-Junior EA. Ethnobotany, phytochemistry and neuropharmacological effects of Petiveriaalliacea L. (Phytolaccaceae): A review.. Journal of ethnopharmacology, 2016 . DOI: 10.1016/j.jep.2016.02.053. [DOI link]
Endpoint study #2: Luz DA., Pinheiro AM., da Silva ML., Monteiro MC., Prediger RD., Ferraz Maia CS., Fontes-Junior EA. Ethnobotany, phytochemistry and neuropharmacological effects of Petiveriaalliacea L. (Phytolaccaceae): A review.. Journal of ethnopharmacology, 2016 . DOI: 10.1016/j.jep.2016.02.053. [DOI link]
Endpoint study #3: Blainski, Andressa., Piccolo, Vanessa K., Mello, Joao Carlos P., de Oliveira, Rubia M. W. Dual effects of crude extracts obtained from Petiveria alliacea L. (Phytolaccaceae) on experimental anxiety in mice . journal of ethnopharmacology, 2010, vol. 128, no. 2, p. 541–544. DOI: 10.1016/j.jep.2010.01.012. [DOI link]
Endpoint study #4: Maia, Carina Scanoni., Teixeira, Valeria Wanderley., Coelho Teixeira, Alvaro Aguiar., Pontes Filho, Nicodemos Teles. Analysis of Fetal and Placental Development in Rats after Administration of Hydroalcoholic Extract from the Root of Petiveria alliacea L. (Phytolaccaceae) . international journal of morphology, 2010, vol. 28, no. 1, p. 165–169. .
Genotox #1: HOYOS, LS., AU, WW., HEO, MY., MORRIS, DL., LEGATOR, MS. EVALUATION OF THE GENOTOXIC EFFECTS OF A FOLK MEDICINE, PETIVERIA-ALLIACEA (ANAMU). MUTATION RESEARCH, 1992, vol. 280, no. 1, p. 29–34. DOI: 10.1016/0165-1218(92)90015-R. [DOI link]