EFSA Compendium of Botanicals

Draft - work in progress

Peperomia pellucida (L.) Kunth

Family:: Piperaceae
Approval state:: Approved
Number of articles retrieved:: 132
Number of processed references:: 6

Compositions

#1: Dillapiole #2: Saponins #3: Tropane alkaloids #4: Tannins #5: Isoquinoline alkaloids #6: Pellucidin A #7: Dillapiole #8: peperomins A, B, C, and E (lignans) #9: Sesamin #10: Apiole #11: Camphor #12: Dillapiole

Endpoint Studies

Genotoxicity

Composition #1: De Lira, P.N.B., Da Silva, J.K.R., Andrade, E.H.A., Sousa, P.J.C., Silva, N.N.S., Maia, J.G.S. Essential oil composition of three Peperomia species from the Amazon, Brazil. natural product communications, 2009, vol. 4, no. 3, p. 427–430. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Dillapiole (RF-00004277-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

55.3
Internal remarks:

Dillapiole

Composition #2: Gini, T.G., Jothi, G.J. Preliminary phytochemical screening of whole plant extracts of peperomia pellucida (linn.) HBK (piperaceae) and marsilea quadrifolia linn. (marsileaceae). International Journal of Pharmacognosy and Phytochemical Research, 2013, vol. 5, no. 3, p. 200–214. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

hexane, acetone,methanol and ethanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #3: Gini, T.G., Jothi, G.J. Preliminary phytochemical screening of whole plant extracts of peperomia pellucida (linn.) HBK (piperaceae) and marsilea quadrifolia linn. (marsileaceae). International Journal of Pharmacognosy and Phytochemical Research, 2013, vol. 5, no. 3, p. 200–214. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol and ethanol
Substance:

Tropane alkaloids (RF-00000245-TOX)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tropane alkaloids

Composition #4: Gini, T.G., Jothi, G.J. Preliminary phytochemical screening of whole plant extracts of peperomia pellucida (linn.) HBK (piperaceae) and marsilea quadrifolia linn. (marsileaceae). International Journal of Pharmacognosy and Phytochemical Research, 2013, vol. 5, no. 3, p. 200–214. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol and ethanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #5: Gini, T.G., Jothi, G.J. Preliminary phytochemical screening of whole plant extracts of peperomia pellucida (linn.) HBK (piperaceae) and marsilea quadrifolia linn. (marsileaceae). International Journal of Pharmacognosy and Phytochemical Research, 2013, vol. 5, no. 3, p. 200–214. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone, methanol and ethanol
Substance:

Isoquinoline alkaloids (RF-00004391-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoquinoline alkaloids

Composition #6: Bayma, JD., Arruda, MSP., Muller, AH., Arruda, AC., Canto, WC. A dimeric ArC2 compound from Peperomia pellucida. PHYTOCHEMISTRY, 2000, vol. 55, no. 7, p. 779–782. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Pellucidin A (lignan-like)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Pellucidin A

Composition #7: da Silva, MHL., Zoghbi, MDB., Andrade, EHA., Maia, JGS. The essential oils of Peperomia pellucida Kunth and P. circinnata Link var. circinnata . flavour and fragrance journal, 1999, vol. 14, no. 5, p. 312–314. DOI: 10.1002/(SICI)1099-1026(199909/10)14:5<312::AID-FFJ835>3.0.CO;2-B. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Dillapiole (RF-00004277-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

39.7
Internal remarks:

Dillapiole

Composition #8: Xu, S., Li, N., Ning, MM., Zhou, CH., Yang, QR., Wang, MW. Bioactive compounds from Peperomia pellucida. journal of natural products, 2006, vol. 69, no. 2, p. 247–250. DOI: 10.1021/np050457s. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

peperomins A, B, C, and E
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, IR, MS, HPLC, Column Chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

peperomins A, B, C, and E (lignans)

Composition #9: Xu, S., Li, N., Ning, MM., Zhou, CH., Yang, QR., Wang, MW. Bioactive compounds from Peperomia pellucida. journal of natural products, 2006, vol. 69, no. 2, p. 247–250. DOI: 10.1021/np050457s. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

asarinin (RF-00004158-PAR)
Additional substance description:

Sesamin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, IR, MS, HPLC, Column Chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Sesamin

Composition #10: Verma, Ram S., Padalia, Rajendra C., Goswami, Prakash., Chauhan, Amit. Essential oil composition of Peperomia pellucida (L.) Kunth from India. JOURNAL OF ESSENTIAL OIL RESEARCH, 2015, vol. 27, no. 2, p. 89–95. DOI: 10.1080/10412905.2014.982878. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

apiole (RF-00003690-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.83
Internal remarks:

Apiole

Composition #11: Verma, Ram S., Padalia, Rajendra C., Goswami, Prakash., Chauhan, Amit. Essential oil composition of Peperomia pellucida (L.) Kunth from India. JOURNAL OF ESSENTIAL OIL RESEARCH, 2015, vol. 27, no. 2, p. 89–95. DOI: 10.1080/10412905.2014.982878. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Drying (dehydration) (A07KG)
Additional extraction description:

hydrodistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.8
Internal remarks:

Camphor

Composition #12: Verma, Ram S., Padalia, Rajendra C., Goswami, Prakash., Chauhan, Amit. Essential oil composition of Peperomia pellucida (L.) Kunth from India. JOURNAL OF ESSENTIAL OIL RESEARCH, 2015, vol. 27, no. 2, p. 89–95. DOI: 10.1080/10412905.2014.982878. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Dillapiole (RF-00004277-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

28.03
Internal remarks:

Dillapiole