EFSA Compendium of Botanicals

Draft - work in progress

Pelargonium graveolens L'Hér.

Family:: Geraniaceae
Approval state:: Approved
Number of articles retrieved:: 601
Number of processed references:: 2

Compositions

#1: myrcene #2: Epigallocatechins #3: Coumaric acid esters

Endpoint Studies

Genotoxicity

Composition #1: Jeon, Ju-Hyun., Kim, Hyung-Wook., Kim, Min-Gi., Lee, Hoi-Seon. Mite-Control Activities of Active Constituents Isolated from Pelargonium graveolens Against House Dust Mites. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2008, vol. 18, no. 10, p. 16661671. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam destilation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

HPLC, GC-MS, EI-MS
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.32
Internal remarks:

myrcene

Composition #2: Al-Sayed, Eman., Martiskainen, Olli., el-Din, Sayed H. Seif., Sabra, Abdel-Nasser A., Hammam, Olfat A., El-Lakkany, Naglaa M. Protective effect of Pelargonium graveolens against carbon tetrachloride-induced hepatotoxicity in mice and characterization of its bioactive constituents by HPLC-PDA-ESI-MS/MS analysis. MEDICINAL CHEMISTRY RESEARCH, 2015, vol. 24, no. 4, p. 14381448. DOI: 10.1007/s00044-014-1218-3. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

epigallocatechins (RF-00010812-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

HPLC-PDA-ESI/MS/MS (TOF)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Epigallocatechins

Composition #3: Al-Sayed, Eman., Martiskainen, Olli., el-Din, Sayed H. Seif., Sabra, Abdel-Nasser A., Hammam, Olfat A., El-Lakkany, Naglaa M. Protective effect of Pelargonium graveolens against carbon tetrachloride-induced hepatotoxicity in mice and characterization of its bioactive constituents by HPLC-PDA-ESI-MS/MS analysis. MEDICINAL CHEMISTRY RESEARCH, 2015, vol. 24, no. 4, p. 14381448. DOI: 10.1007/s00044-014-1218-3. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

coumaric acid esters (RF-00010798-PAR)
Additional substance description:

Coumaric acid hexose and pentose esters
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

HPLC-PDA-ESI/MS/MS (TOF)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumaric acid esters