EFSA
ecomole
vscht
  2. Yam bean (as plant) // Pachyrhizus erosus (L.) Urb.

Yam bean (as plant) // Pachyrhizus erosus (L.) Urb.

Family:
Fabaceae
Approval state:
Approved
Number of articles retrieved:
244
Number of processed references:
8
Compositions
#1: L-(+)-abrine #2: kaikasaponin III, phaseoside IV #3: Daidzin #4: pachyrrhizone #5: 3-​phenylfuranocoumarins (III and IV) #6: Rotenone #7: Rotenone #8: Pachyrrhizine #9: Isoflavonoids
Endpoint Studies
#1: Mortality resulting from asphyxia from Yam bean or Rotenone toxicity #2: Yam bean seed poisoning can cause acute metabolic acidosis and altered mental status, which could be confused with acute cyanide intoxication from a cyanogenic glycoside-containing plant
Genotoxicity
#1: Rotenone genotoxicity was detected using the comet assay
Composition #1: Yahara, Shoji., Irino, Nobuto., Takaoka, Tsuneo., Nohara, Toshihiro. Studies on the constituents of Pachyrhizus erosus. Natural Medicines, 1994, vol. 48, no. 4, p. 312–313. .
Composition #2: Yahara, Shoji., Irino, Nobuto., Takaoka, Tsuneo., Nohara, Toshihiro. Studies on the constituents of Pachyrhizus erosus. Natural Medicines, 1994, vol. 48, no. 4, p. 312–313. .
Composition #3: Yahara, Shoji., Irino, Nobuto., Takaoka, Tsuneo., Nohara, Toshihiro. Studies on the constituents of Pachyrhizus erosus. Natural Medicines, 1994, vol. 48, no. 4, p. 312–313. .
Composition #4: Baker, Bella Y., Lynn, E. V. Examination of the seed of Pachyrrhizus erosus. journal of the american pharmaceutical association, None, p. 117–118. .
Composition #5: Krishnamurti, M., Seshadri, T. R. Chemical components of yam beans; their evolution and interrelation. current science, 1966, p. 167–169. .
Composition #6: Lautie, E., Rozet, E., Hubert, P., Leclercq, J. Quetin. Quantification of rotenone in seeds of different species of yam bean (Pachyrhizus sp.) by a SPE HPLC-UV method. FOOD CHEMISTRY, 2012, vol. 131, no. 4, p. 1531–1538. DOI: 10.1016/j.foodchem.2011.09.125. [DOI link]
Composition #7: Lautie, E., Rozet, E., Hubert, P., Vandelaer, N., Billard, F., Zum Felde, T., Grueneberg, W. J., Quetin-Leclercq, J. Fast method for the simultaneous quantification of toxic polyphenols applied to the selection of genotypes of yam bean (Pachyrhizus sp.) seeds. TALANTA, 2013, vol. 117, p. 94–101. DOI: 10.1016/j.talanta.2013.08.038. [DOI link]
Composition #8: Lautie, E., Rozet, E., Hubert, P., Vandelaer, N., Billard, F., Zum Felde, T., Grueneberg, W. J., Quetin-Leclercq, J. Fast method for the simultaneous quantification of toxic polyphenols applied to the selection of genotypes of yam bean (Pachyrhizus sp.) seeds. TALANTA, 2013, vol. 117, p. 94–101. DOI: 10.1016/j.talanta.2013.08.038. [DOI link]
Composition #9: Estrella-Parra, Edgar A., Gomez-Verjan, Juan C., Gonzalez-Sanchez, Ignacio., Ricardo Vazquez-Martinez, Edgar., Vergara-Castaneda, Edgar., Cerbon, Marco A., Alavez-Solano, Dagoberto., Reyes-Chilpa, Ricardo. Rotenone isolated from Pachyrhizus erosus displays cytotoxicity and genotoxicity in K562 cells. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 20, p. 1780–1785. DOI: 10.1080/14786419.2014.939081. [DOI link]
Endpoint study #1: Narongchai, Paitoon., Narongchai, Siripun., Thampituk, Suparat. The first fatal case of yam bean and rotenone toxicity in Thailand. Journal of the Medical Association of Thailand, 2005, vol. 88, no. 7, p. 984–987. .
Endpoint study #2: Hung, Y.-M., Hung, S.-Y., Olson, K. R., Chou, K.-J., Lin, S.-L., Chung, H.-M., Tung, C.-N., Chang, J.-C. Yam bean seed poisoning mimicking cyanide intoxication. Internal Medicine Journal, 2007, p. 130–132. .
Genotox #1: Estrella-Parra, Edgar A., Gomez-Verjan, Juan C., Gonzalez-Sanchez, Ignacio., Ricardo Vazquez-Martinez, Edgar., Vergara-Castaneda, Edgar., Cerbon, Marco A., Alavez-Solano, Dagoberto., Reyes-Chilpa, Ricardo. Rotenone isolated from Pachyrhizus erosus displays cytotoxicity and genotoxicity in K562 cells. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 20, p. 1780–1785. DOI: 10.1080/14786419.2014.939081. [DOI link]