EFSA Compendium of Botanicals

Draft - work in progress

Pachira nut (as plant) // Pachira aquatica Aubl.

Family:: Malvaceae
Approval state:: Approved
Number of articles retrieved:: 137
Number of processed references:: 1

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Oliveira, JTA., Vasconcelos, IM., Bezerra, LCNM., Silveira, SB., Monteiro, ACO., Moreira, RA. Composition and nutritional properties of seeds from Pachira aquatica Aubl, Sterculia striata St Hil et Naud and Terminalia catappa Linn . food chemistry, 2000, vol. 70, no. 2, p. 185–191. DOI: 10.1016/S0308-8146(00)00076-5. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aqueous extract
Substance:

Lectins (RF-00000439-ORG)
Additional substance description:

Lectin expressed as haemagglutinating units x 10-3 per kg seed flour.
Analytical method code:

Electrophoretical tests (F070A)
Result unit:

Unit (G005A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

113
Internal remarks:

Lectins

Endpoint study #1: Oliveira, JTA., Vasconcelos, IM., Bezerra, LCNM., Silveira, SB., Monteiro, ACO., Moreira, RA. Composition and nutritional properties of seeds from Pachira aquatica Aubl, Sterculia striata St Hil et Naud and Terminalia catappa Linn . food chemistry, 2000, vol. 70, no. 2, p. 185–191. DOI: 10.1016/S0308-8146(00)00076-5. [DOI link]

Study relevance:

Human health
Plant part:

Seed (as part-nature) (A066P)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

aqueous extract
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Enzyme inhibition (CHD067EP)
Concentration unit:

Gram/kilogram (G015A)
Effect concentration:

2.6
Critical effect:

Digestive (TOX18A)
Target tissue:

digestive: Pancreas (TT024A)
Effect description:

trypsin inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

trypsin inhibition

Endpoint study #2: Oliveira, JTA., Vasconcelos, IM., Bezerra, LCNM., Silveira, SB., Monteiro, ACO., Moreira, RA. Composition and nutritional properties of seeds from Pachira aquatica Aubl, Sterculia striata St Hil et Naud and Terminalia catappa Linn . food chemistry, 2000, vol. 70, no. 2, p. 185–191. DOI: 10.1016/S0308-8146(00)00076-5. [DOI link]

Study relevance:

Human health
Plant part:

Seed (as part-nature) (A066P)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

aqueous extract
Type of toxicological test:

short-term toxicity (CHD017TT)
Tested organism:

Rat (as animal) (A0CNV)
Strain of test organism:

Wistar (CHD013ST)
Sex:

Male
Route of exposure:

ORAL: FEED (OECD2230PL)
Exposure duration:

10.0
Unit of exposure duration:

Day (G134A)
Number of organisms dosed:

6
Control groups used:

yes
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

NOT REPORTED (TOX17A)
Effect description:

enlargement of the stomach, liver, pancreas, kidneys, heart and lungs; spleen atrophy
Effect or parameter linked to the endpoint:

organ weights (CHD012BE)
Internal remarks:

highly toxic