Draft - work in progress
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- Onopordum acanthium L.
Onopordum acanthium L.
- Family:
- Asteraceae
- Approval state:
- Approved
- Number of articles retrieved:
- 177
- Number of processed references:
- 8
Composition #1: Lajter I., Pan SP., Nikles S., Ortmann S., Vasas A., Csupor-Loffler B., Forgo P., Hohmann J., Bauer R. Inhibition of COX-2 and NF-kappaB1 Gene Expression, NO Production, 5-LOX, andCOX-1 and COX-2 Enzymes by Extracts and Constituents of Onopordum acanthium.. Planta medica, 2015, vol. 81, no. 14, p. 1270–6. DOI: 10.1055/s-0035-1546242.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH
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Substance:
lignans (RF-00004361-PAR)
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Additional substance description:
pinoresinol, syringaresinol, and medioresinol
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Lignans
Composition #2: Lajter I., Pan SP., Nikles S., Ortmann S., Vasas A., Csupor-Loffler B., Forgo P., Hohmann J., Bauer R. Inhibition of COX-2 and NF-kappaB1 Gene Expression, NO Production, 5-LOX, andCOX-1 and COX-2 Enzymes by Extracts and Constituents of Onopordum acanthium.. Planta medica, 2015, vol. 81, no. 14, p. 1270–6. DOI: 10.1055/s-0035-1546242.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH
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Substance:
Sesquiterpene lactones (RF-00004319-PAR)
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Additional substance description:
zaluzanin C and 4β,15,11β,13-tetrahydrozaluzanin C
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Sesquiterpene lactones
Composition #3: Kang, Ting-Guo., Kawamura, Tomoko., Noro, Yukio., Tanaka, Toshihiro. Pharmacognostical evaluation of Arctii Fructus (2): Adulteration on the Chinese commercial samples. Natural Medicines, 1999, vol. 53, no. 4, p. 206–208. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH
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Substance:
furan derivatives (RF-00004396-PAR)
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Additional substance description:
Arctiin
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Furan derivatives
Composition #4: Bogs, H. U., Bogs, U. Constituents of Onopordum acanthium. I. Coumarins and flavones. pharmazie, 1965, p. 706–709. .
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Plant part:
Unspecified (A07XD)
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Additional extraction description:
unspecified
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
Aesculin
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Coumarins (Aesculin)
Composition #5: Bogs, Hans U., Bogs, Ulrich. Constituents of Onopordum acanthium. II. Flavonoids, tannins, and betaines. pharmazie, 1967, p. 54–58. .
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Plant part:
Unspecified (A07XD)
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Additional extraction description:
unspecified
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Substance:
Tannins (RF-00004337-PAR)
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Additional substance description:
caffeic hydroxamate and a tannin-like compound
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Tannins
Composition #6: Drozdz, B., Holub, M., Samek, Z., Herout, V., Sorm, F. Terpenes. CXCII. The constitution and absolute configuration of onopordopicrine, a sesquiterpenic lactone from Onopordon acanthium. collection of czechoslovak chemical communications, 1968, p. 1730–1737. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
Sesquiterpene lactones (RF-00004319-PAR)
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Additional substance description:
Onopordopicrine
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Onopordopicrine
Composition #7: Ul'chenko, N.T., Gusakova, S.D., Glushenkova, A.I. Oxygenated acids of the lipids of Onopordum acanthium seeds. chemistry of natural compounds, 1993, vol. 29, no. 4, p. 447–450. DOI: 10.1007/BF00630567.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
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Additional extraction description:
seed oil (hydrolysed to obtain fatty acids)
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Substance:
epoxides (RF-00010829-PAR)
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Additional substance description:
Triepoxy acids of C18 series
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
Spectroscopy, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Fatty acids (triepoxy)
Composition #8: Tyumkina, T. V., Nuriev, I. F., Khalilov, L. M., Akhmetova, V. R., Dzhemilev, U. M. PMR and (13)C NMR spectra of biologically active compounds. XIII.* Structure and stereochemistry of a new phenylpropanoid glycoside isolated from Onopordum acanthium seeds . chemistry of natural compounds, 2009, vol. 45, no. 1, p. 61–65. DOI: 10.1007/s10600-009-9254-9.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
chloroform
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Substance:
phenylpropanoids (RF-00004367-PAR)
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
Spectroscopy (HHCOSY, HSBC, HMBC, ROESY)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Phenylpropanoids
Composition #9: Watanabe, Yusuke., Novaes, Paula., Varela, Rosa M., Molinillo, Jose M. G., Kato-Noguchi, Hisashi., Macias, Francisco A. Phytotoxic Potential of Onopordum acanthium L. (Asteraceae). CHEMISTRY & BIODIVERSITY, 2014, vol. 11, no. 8, p. 1247–1255. DOI: 10.1002/cbdv.201400070.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Hexane: EtOAc (4:6)
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Substance:
Sesquiterpene lactones (RF-00004319-PAR)
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Additional substance description:
elemanolide and acanthiolide
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Sesquiterpene lactones