Draft - work in progress
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- Oldenlandia corymbosa L. // Hedyotis corymbosa (L.) Lam.
Oldenlandia corymbosa L. // Hedyotis corymbosa (L.) Lam.
- Family:
- Rubiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 182
- Number of processed references:
- 6
Composition #1: Yadav, R. N. S., Agarwala, Munin. Phytochemical analysis of some medicinal plants. journal of phytology, 2011, p. 10–14. .
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
hot water extraction, also extraction in methanol, ethanol, and acetone
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Alkaloids
Composition #2: Kuang, L.-S., Jiang, W., Hou, A.-J., Qian, M. Chemical constituents of Hedyotis corymbosa. chinese traditional and herbal drugs, 2009, vol. 40, no. 7, p. 1020–1024. .
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Plant part:
Live plants (as part-nature) (A0BA0)
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Additional extraction description:
unspecified
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Substance:
Esculetin (RF-00003667-PAR)
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
structure determination by spectroscopic methods (not specified)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Esculetin
Composition #3: Kuang, L.-S., Jiang, W., Hou, A.-J., Qian, M. Chemical constituents of Hedyotis corymbosa. chinese traditional and herbal drugs, 2009, vol. 40, no. 7, p. 1020–1024. .
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Plant part:
Live plants (as part-nature) (A0BA0)
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Additional extraction description:
unspecified
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Substance:
3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
structure determination by spectroscopic methods (not specified)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Protocatechuic acid
Composition #4: Kuang, L.-S., Jiang, W., Hou, A.-J., Qian, M. Chemical constituents of Hedyotis corymbosa. chinese traditional and herbal drugs, 2009, vol. 40, no. 7, p. 1020–1024. .
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Plant part:
Live plants (as part-nature) (A0BA0)
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Additional extraction description:
unspecified
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Substance:
scopoletin (RF-00004048-PAR)
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
structure determination by spectroscopic methods (not specified)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Scopoletin
Composition #5: Li, H., Li, C., Xia, B., Zhou, Y., Lin, L., Liao, D. A chemotaxonomic study of phytochemicals in Hedyotis corymbosa. biochemical systematics and ecology, 2015, vol. 62, p. 173–177. DOI: 10.1016/j.bse.2015.06.028.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol (70%)
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Substance:
anthraquinones (RF-00004343-PAR)
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Additional substance description:
1-methoxy-2-hydroxyanthraquinone
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Anthraquinones
Composition #6: Li, H., Li, C., Xia, B., Zhou, Y., Lin, L., Liao, D. A chemotaxonomic study of phytochemicals in Hedyotis corymbosa. biochemical systematics and ecology, 2015, vol. 62, p. 173–177. DOI: 10.1016/j.bse.2015.06.028.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ethanol (70%)
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
hedyotiscone A
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Coumarins
Composition #7: Awobajo, F O., Omorodion-Osagie, E., Olatunji-Bello, I I., Adegoke, O A., Adeleke, T I. Acute oral toxicity test and phytochemistry of some West African medicinal plants. . nigerian quarterly journal of hospital medicine, 2009, vol. 19, no. 1, p. 53–8. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
cardiac glycosides (RF-00010823-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Cardiac glycosides
Composition #8: Awobajo, F O., Omorodion-Osagie, E., Olatunji-Bello, I I., Adegoke, O A., Adeleke, T I. Acute oral toxicity test and phytochemistry of some West African medicinal plants. . nigerian quarterly journal of hospital medicine, 2009, vol. 19, no. 1, p. 53–8. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins
Composition #9: Awobajo, F O., Omorodion-Osagie, E., Olatunji-Bello, I I., Adegoke, O A., Adeleke, T I. Acute oral toxicity test and phytochemistry of some West African medicinal plants. . nigerian quarterly journal of hospital medicine, 2009, vol. 19, no. 1, p. 53–8. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
Tannins (RF-00004337-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Tannins
Composition #10: Noiarsa, Pawadee., Ruchirawat, Somsak., Otsuka, Hideaki., Kanchanapoom, Tripetch. Chemical constituents from Oldenlandia corymbosa L. of Thai origin. JOURNAL OF NATURAL MEDICINES, 2008, vol. 62, no. 2, p. 249–250. DOI: 10.1007/s11418-007-0212-1.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH, H2), EtOAc
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Substance:
lignans (RF-00004361-PAR)
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Additional substance description:
(+)-lyoniresinol-3α-O-β-glucopyranoside
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Lignans
Endpoint study
#1: Nikolajsen, Tine., Nielsen, Frank., Rasch, Vibeke., Sorensen, Pernille H., Ismail, Flora., Kristiansen, Uffe., Jager, Anna K. Uterine contraction induced by Tanzanian plants used to induce abortion. journal of ethnopharmacology, 2011, vol. 137, no. 1, p. 921–925. DOI: 10.1016/j.jep.2011.05.026.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Type of toxicological test:
other (CHD008TT)
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Tested organism:
Rat (as animal) (A0CNV)
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Strain of test organism:
Sprague-Dawley (CHD012ST)
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Endpoint measured:
Concentration level (CHD013EP)
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Concentration unit:
Milligram/millilitre (G191A)
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Effect concentration:
0.04-1.40
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Critical effect:
REPRODUCTIVE (TOX05A)
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Target tissue:
urogenital: Uterus (TT052A)
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Effect description:
Plant extracts induced strong contractions of the uterus, and can be used to induce an abortion
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Effect or parameter linked to the endpoint:
reproduction (CHD014BE)
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Internal remarks:
induces strong contractions of the uterus
