EFSA Compendium of Botanicals

Draft - work in progress

Olax psittacorum (Lam.) Vahl

Family:: Olacaceae
Approval state:: Approved
Number of articles retrieved:: 5
Number of processed references:: 2

Compositions

#1: olaxoside #2: alkaloids (leaves) #3: tannins #4: alkaloids (bark) #5: olaxoside - leaves #6: olaxoside - roots #7: olaxoside - bark

Endpoint Studies

#1: Mice LD50 #2: laxative

Genotoxicity

Composition #1: Forgacs, P., Buffard, G., Desconclois, J. F., Jehanno, A., Provost, J., Tiberghien, R., Touche, A. Phytochemical studies and biological activities of plants endemic of the islands of Reunion and Mauritius. Plantes Medicinales et Phytotherapie, 1981, p. 80–91. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Olaxoside (RF-00010965-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

olaxoside

Composition #2: Forgacs, P., Buffard, G., Desconclois, J. F., Jehanno, A., Provost, J., Tiberghien, R., Touche, A. Phytochemical studies and biological activities of plants endemic of the islands of Reunion and Mauritius. Plantes Medicinales et Phytotherapie, 1981, p. 80–91. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

420
Internal remarks:

alkaloids (leaves)

Composition #3: Forgacs, P., Buffard, G., Desconclois, J. F., Jehanno, A., Provost, J., Tiberghien, R., Touche, A. Phytochemical studies and biological activities of plants endemic of the islands of Reunion and Mauritius. Plantes Medicinales et Phytotherapie, 1981, p. 80–91. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #4: Forgacs, P., Buffard, G., Desconclois, J. F., Jehanno, A., Provost, J., Tiberghien, R., Touche, A. Phytochemical studies and biological activities of plants endemic of the islands of Reunion and Mauritius. Plantes Medicinales et Phytotherapie, 1981, p. 80–91. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

380
Internal remarks:

alkaloids (bark)

Composition #5: FORGACS, P., PROVOST, J. OLAXOSIDE, A SAPONIN FROM OLAX-ANDRONENSIS, OLAX-GLABRIFLORA AND OLAX-PSITTACORUM. PHYTOCHEMISTRY, 1981, vol. 20, no. 7, p. 1689–1691. DOI: 10.1016/S0031-9422(00)98556-X. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Olaxoside (RF-00010965-PAR)
Analytical method code:

GC-FID (F040A)
Analytical method - additional description:

1H NMR; 13C NMR; IR; UV; TLC
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10
Internal remarks:

olaxoside - leaves

Composition #6: FORGACS, P., PROVOST, J. OLAXOSIDE, A SAPONIN FROM OLAX-ANDRONENSIS, OLAX-GLABRIFLORA AND OLAX-PSITTACORUM. PHYTOCHEMISTRY, 1981, vol. 20, no. 7, p. 1689–1691. DOI: 10.1016/S0031-9422(00)98556-X. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Olaxoside (RF-00010965-PAR)
Analytical method code:

GC-FID (F040A)
Analytical method - additional description:

1H NMR; 13C NMR; IR; UV; TLC
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1
Internal remarks:

olaxoside - roots

Composition #7: FORGACS, P., PROVOST, J. OLAXOSIDE, A SAPONIN FROM OLAX-ANDRONENSIS, OLAX-GLABRIFLORA AND OLAX-PSITTACORUM. PHYTOCHEMISTRY, 1981, vol. 20, no. 7, p. 1689–1691. DOI: 10.1016/S0031-9422(00)98556-X. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Olaxoside (RF-00010965-PAR)
Analytical method code:

GC-FID (F040A)
Analytical method - additional description:

1H NMR; 13C NMR; IR; UV; TLC
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3
Internal remarks:

olaxoside - bark

Endpoint study #1: FORGACS, P., PROVOST, J. OLAXOSIDE, A SAPONIN FROM OLAX-ANDRONENSIS, OLAX-GLABRIFLORA AND OLAX-PSITTACORUM. PHYTOCHEMISTRY, 1981, vol. 20, no. 7, p. 1689–1691. DOI: 10.1016/S0031-9422(00)98556-X. [DOI link]

Study relevance:

Human health
Plant part:

Live plants (as part-nature) (A0BA0)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Type of toxicological test:

not reported (CHD015TT)
Tested organism:

House mouse (as animal) (A0CNT)
Sex:

No data
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Control groups used:

no data
Endpoint measured:

Dose producing lethality in 50% of experimental organisms (CHD024EP)
Concentration unit:

Gram/kilogram (G015A)
Effect concentration:

2
Critical effect:

NOT REPORTED (TOX17A)
Target tissue:

Digestive (TT002A)
Effect description:

laxative effect; little toxicity
Effect or parameter linked to the endpoint:

no data (CHD002BE)
Internal remarks:

Mice LD50

Endpoint study #2: FORGACS, P., PROVOST, J. OLAXOSIDE, A SAPONIN FROM OLAX-ANDRONENSIS, OLAX-GLABRIFLORA AND OLAX-PSITTACORUM. PHYTOCHEMISTRY, 1981, vol. 20, no. 7, p. 1689–1691. DOI: 10.1016/S0031-9422(00)98556-X. [DOI link]

Study relevance:

Human health
Substance:

Olaxoside (RF-00010965-PAR)
Type of toxicological test:

not reported (CHD015TT)
Tested organism:

House mouse (as animal) (A0CNT)
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Endpoint measured:

Dose level (CHD014EP)
Concentration unit:

Milligram/kilogram (G061A)
Effect concentration:

25-50
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

laxative
Effect or parameter linked to the endpoint:

no data (CHD002BE)
Internal remarks:

laxative