EFSA Compendium of Botanicals

Draft - work in progress

Ochrosia borbonica J.F.Gmel.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 16
Number of processed references:: 3

Compositions

#1: Alkaloids #2: Indole alkaloids #3: Alkaloids

Endpoint Studies

Genotoxicity

Composition #1: Le Men, J., Hayat, M., Mathe, G., Guillon, J. C., Chenu, E., Humblot, M., Masson, Y. Methoxy-9-ellipticine lactate. I. Experimental study (oncostatic and immunosupressive actions; preclinical pharmacology). revue europeenne d'etudes cliniques et biologiques, 1970, p. 534–538. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Methoxy-9-ellipticine lactate
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #2: Zhang, Bing-Jie., Yan, Ju-Ming., Wu, Zi-Kun., Liu, Ya-Ping., Bao, Mei-Fen., Cheng, Gui-Guang., Luo, Xiao-Dong., Cai, Xiang-Hai., Li, Yan. Alkaloids from Ochrosia borbonica. helvetica chimica acta, 2013, vol. 96, no. 12, p. 2288–2298. DOI: 10.1002/hlca.201300136. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

indole alkaloids (RF-00004503-PAR)
Additional substance description:

ochroborines A and B,10-hydroxyisovallesiachotamine, 10-hydroxyisositsirikine, 10,11-dimethoxysitsirikine,10-methoxyapoyohimbine,10-hydroxyakuammidine, akuammidine 17-O-b-d-glucoside, 15a-hydroxyapparicine and 15a-hydroxy-10-methoxyapparicine
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Indole alkaloids

Composition #3: SVOBODA, GH., POORE, GA., MONTFORT, ML. ALKALOIDS OF OCHROSIA MACULATA JACQ (OCHROSIA BORBONICA GMEL). journal of pharmaceutical sciences, 1968, vol. 57, no. 10, p. 1720–&. DOI: 10.1002/jps.2600571019. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

benzene
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

9-methoxyellipticine
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids