EFSA Compendium of Botanicals

Draft - work in progress

Nymphaea nouchali var. caerulea (Savigny) Verdc. // Nymphaea caerulea Savigny

Family:: Nymphaeaceae
Approval state:: Approved
Number of articles retrieved:: 180
Number of processed references:: 4

Compositions

#1: Total tannins #2: Alkaloids #3: Tannins #4: Lectin

Endpoint Studies

Genotoxicity

Composition #1: Parimala, Mabel., Shoba, Francis Gricilda. Phytochemical analysis and in vitro antioxidant acitivity of hydroalcoholic seed extract of Nymphaea nouchali Burm. f. . asian pacific journal of tropical biomedicine, 2013, vol. 3, no. 11, p. 887–895. DOI: 10.1016/S2221-169(13)60174-4. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

Tannins (RF-00004337-PAR)
Substance used for equivalence:

gallic acid (RF-00003821-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

195.8
Internal remarks:

Total tannins

Composition #2: Lakshmi, G., Smitha, N., Ammu, S.V., Priya, C.L., Bhaskara Rao, K.V. Phytochemical profile, in vitro antioxidant and hemolytic activities of various leaf extract of Nymphaea Nouchali Linn: An in vitro study. international journal of pharmacy and pharmaceutical sciences, 2014, vol. 6, no. 6, p. 548–552. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether, chloroform, methanol, and distilled water.
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #3: Lakshmi, G., Smitha, N., Ammu, S.V., Priya, C.L., Bhaskara Rao, K.V. Phytochemical profile, in vitro antioxidant and hemolytic activities of various leaf extract of Nymphaea Nouchali Linn: An in vitro study. international journal of pharmacy and pharmaceutical sciences, 2014, vol. 6, no. 6, p. 548–552. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether, chloroform, methanol, and distilled water.
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #4: Kabir, Syed Rashel., Abu Zubair, Md., Nurujjaman, Md., Haque, Md. Azizul., Hasan, Imtiaj., Islam, Md. Farhadul., Hossain, Md. Tanvir., Hossain, Md. Anowar., Rakib, Md. Abdur., Alam, Mohammad Taufiq., Shaha, Ranajit Kumar., Hossain, Md. Tofazzal., Kimura, Yoshinobu., Absar, Nurul. Purification and characterization of a Ca2+-dependent novel lectin from Nymphaea nouchali tuber with antiproliferative activities . bioscience reports, 2011, vol. 31, no. 6, p. 465–475. DOI: 10.1042/BSR20100126. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts used as staple food (as part-nature) (A0F5F)
Additional extraction description:

unspecified
Substance:

Lectins (RF-00000439-ORG)
Additional substance description:

an o-nitrophenyl beta-D-galactopyranoside sugar-specific lectin
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

anion-exchange chromatography on DEAE-cellulose, hydrophobic chromatography on Hi Trap Phenyl HP and by repeated anion-exchange chromatography on Hi Trap Q FF column
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lectin

Endpoint study #1: Simonienko, K., Waszkiewicz, N., Szulc, A. Psychoactive plant species - Actual list of plants prohibited in Poland Roślinne środki odurzajace - Aktualnie obowiazujaca lista w Polsce . psychiatria polska, 2013, vol. 47, no. 3, p. 499–510. .

Study relevance:

Human health
Substance:

Aporphine alkaloids (RF-00010806-PAR)
Plant part:

Unspecified (A07XD)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

water or ethanol
Type of toxicological test:

other (CHD008TT)
Tested organism:

Human (as organism) (A056J)
Sex:

No data
Route of exposure:

ORAL: DRINKING WATER (OECD2229PL)
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

NEUROTOXICITY (TOX04A)
Target tissue:

neurologic: Brain (TT034A)
Effect description:

psychoactive alkaloids: agonistic dopaminergic receptor
Effect or parameter linked to the endpoint:

neurology (CHD027BE)
Internal remarks:

Psychoactive aporphine alkaloids