EFSA Compendium of Botanicals

Draft - work in progress

Mirabilis jalapa L.

Family:: Nyctaginaceae
Approval state:: Approved
Number of articles retrieved:: 564
Number of processed references:: 6

Compositions

#1: Betaxanthin I, indicaxanthin, miraxanthins I to V, vulgaxanthin I #2: Trigonelline #3: Chrysophanol #4: Alkaloids #5: Calcium oxalates #6: Tannins #7: Miraxanthin I, III and V; vulgaxanthin II #8: Trigonelline

Endpoint Studies

Genotoxicity

Composition #1: Piattelli, M., Minale, L., Nicolaus, R. A. Pigments of centrospermae. V. Betaxanthins from Mirabilis jalapa. Phytochemistry (Elsevier), 1965, p. 817–823. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

cold MeOH.
Substance:

Betalains (RF-00010820-PAR)
Additional substance description:

Betaxanthin I, indicaxanthin, miraxanthins I to V, vulgaxanthin I
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Betaxanthin I, indicaxanthin, miraxanthins I to V, vulgaxanthin I

Composition #2: Song, Fenyun., Zhang, Dezhi., Zhong, Yunxiang., Wang, Wei., Zeng, Shaohui. Content determination of trigonelline in root of Mirabilis jalapa by reversed phase HPLC. zhongyao xinyao yu linchuang yaoli, 2005, p. 189–191. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

trigonelline (RF-00004092-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Trigonelline

Composition #3: Kuang, Jiale., Zhang, Dezhi. Chemical constituents of the root of Mirabilis jalapa. guangdong yaoxueyuan xuebao, 2007, p. 1–2. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol-petroleum ether
Substance:

chrysophanol (RF-00003737-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Chrysophanol

Composition #4: Nath, L.R., Manjunath, K.P., Savadi, R.V., Akki, K.S. Pharmacognostical and phytochemical studies of Mirabilis jalapa Linn. leaves. pharmacognosy journal, 2009, vol. 1, no. 2, p. 111–115. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

alcohol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #5: Nath, L.R., Manjunath, K.P., Savadi, R.V., Akki, K.S. Pharmacognostical and phytochemical studies of Mirabilis jalapa Linn. leaves. pharmacognosy journal, 2009, vol. 1, no. 2, p. 111–115. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Fresh (A166Y)
Substance:

Calcium oxalate (RF-00003960-PAR)
Analytical method code:

Microscopic detection (F536A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calcium oxalates

Composition #6: Nath, L.R., Manjunath, K.P., Savadi, R.V., Akki, K.S. Pharmacognostical and phytochemical studies of Mirabilis jalapa Linn. leaves. pharmacognosy journal, 2009, vol. 1, no. 2, p. 111–115. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

alcohol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #7: Gandia-Herrero, F., Garcia-Carmona, F., Escribano, J. Fluorescent pigments: New perspectives in betalain research and applications. FOOD RESEARCH INTERNATIONAL, 2005, vol. 38, no. 8-9, p. 879–884. DOI: 10.1016/j.foodres.2005.01.012. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Phosphate buffer sol.
Substance:

Betalains (RF-00010820-PAR)
Additional substance description:

Miraxanthin I, III and V; vulgaxanthin II
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Miraxanthin I, III and V; vulgaxanthin II

Composition #8: Ashihara, Hiroshi., Watanabe, Shin. Accumulation and Function of Trigonelline in Non-leguminous Plants. natural product communications, 2014, vol. 9, no. 6, p. 795–798. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

trigonelline (RF-00004092-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Millimol/100 Gramm (G193A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.03-1.3
Internal remarks:

Trigonelline